Mrs. Greenwood, age 62 years, was diagnosed 5 years ago with hypertension. Her body mass index (BMI) is 33.8 (weight = 185 lb; height = 62 inches). Her blood pressure readings at the physician’s office range from 220/104 to 176/92, despite treatment with valsartan-hydrochlorothiazide (Diovan-HCT 160/25).