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What is meant when we say that certain bacteria are antibiotic- resistant?

What is meant when we say that certain bacteria are antibiotic-

resistant? Explain how the use of antibiotics  for the past fifty 

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years has led to the development of antibiotic-resistant strains of 

bacteria.  What are some 

 precautions that can be taken to slow down the development of 

antibiotic-resistance?  

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