Mechanisms of EX‡ stabilization 3: Electrostatic Catalysis O OH O…
Mechanisms of EX‡ stabilization 3: Electrostatic Catalysis O OH O…
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Mechanisms of EX‡ stabilization 3: Electrostatic Catalysis O OH O OEt H2O EtOH O OEt d – d O H H tetrahedral intermediate N C O N C O H d – d – Backbone of enzyme d Hd Fixed charges on in the enzyme active site are effective at stabilizing charges in the transition state
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