Powerpoint 4-5 slides with narrative in speaker notes

Topic: Develop a brief PowerPoint presentation (4–5 slides) that will acquaint your classmates with the test/assessment of your choice. In the Notes section of presentation, include a narrative explaining each slide.

Each slide should contain at least 3 bullet points. Focus on elements of the assessment that you would like to learn more about. You may use the same test for your Test Critique due in Module/Week 7. You may find tests by viewing the publisher web sites, Pearson Assessment or Multi Health Systems. They provide all the information you need for the assignment e.g., what the test is used for, population served, time to complete, cost, etc.

Select a test that you are knowledge about and can write a future paper on! I would like you to select the  Wechsler scales. It is also called the WAIS-IV which is Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV).

Core Values In Mental Health Nursing Nursing Essay

The Department of Health (DOH 2006) recognises that mental health nurses are the largest profession working within the field of mental health today. In the Chief Nursing Officer’s (CNO 2006), review it recommends that, it is essential for mental health nurses to incorporate the broad principles of core values when carrying out care (DOH 2006). This essay will focus on the key principles of core values of equality and diversity, evidence based practice and the recovery approach. The significance of these within the field of mental health nursing will be discussed. Finally it will explain how these core values impact on people who experience symptoms of psychosis.

According to The Nursing and Midwifery council (NMC 2008) the core principles when carrying out care are to treat people as in individuals and respect their privacy and dignity; not to discriminate in any way against those who are receiving care; to collaborate with others is essential to protect; and promote the health and well-being of those receiving care, their families, carers and people in the wider community. It is imperative to provide a high standard of practice and care at all times. Acting with integrity and being open and honest is vital to uphold the reputation of the nursing profession.

The DOH (2006) recognises equality in health care is imperative to ensure that each person has an equal opportunity to have their needs met. People should be treated the same no matter what their race, gender, disability, age or sexual orientation is (Equality Act 2010). The CNO (2006) says that being equal is not necessarily being the same it is vital that nurses understand the meaning of “Difference and “Diversity” both these promote equality.

The DOH (2010) has set a new framework called “New Horizons” to enable nurses to consider the vulnerable groups of people they care for and aim to provide a high quality of care. One group considered vulnerable is people who experience symptoms of psychosis.

Schizophrenia lies within the category of psychosis (Tsuang et al 2000). Stigma surrounds the term schizophrenia and these misconceptions have lead to much confusion and misunderstanding. Media highlights images of frightening behaviour and violence that leads to stereotyping people with schizophrenia (Byrne 2000). The world Health Organisation (2010) identified schizophrenia as the top ten most debilitating disorders affecting humans. The Disability Discrimination Act (DDA 1995), recognises that a disability is a physical or mental impairment and people with a diagnosis of schizophrenia are covered by the legislation. According to Sayce (2001), the dilemma for these people is whether they wear the label of their diagnosis, or hide it, and lose their civil rights.

The DOH (2010) identifies that stigma and discrimination-surrounding mental illness can be extremely difficult for these people to maintain friendships, seek employment, education and be involved in their community. People with mental health problems are one of the most socially excluded groups. Therefore, it is imperative that nurses work collaboratively to enable them to overcome the difficulties they face.

Working collaboratively with people when implementing evidence based interventions is vital. Evidence Based practice (EBP) is the integration of best available research evidence with clinical expertise and patients values (Sackett et al 2000). Nelson (2010) recognises that there are five steps that involve the process of EBP. These are asking questions to identify the patient’s needs; critique the quality of evidence; apply the evidence in practice; then evaluate the outcomes that are relevant to meeting the client’s needs. According to McKenna et al (2000) EBP does not stop at the implementation stage as to use evidence to under pin practice and not evaluate the effectiveness is short sighted.

There are various sources of evidence some of these are traditional findings these are not research based. They are passed down from one generation of nurses to another and can be considered to do more harm than good. It is felt that the interventions are being carried out because they have always been done that way (McKenna et al 1999). The other types are experience, intuition, service users and their families, audit, protocols and guidelines, research studies, authorities and experts, systematic reviews and randomised control trials (Brooker & Waugh 2007). Many professions consider randomised control trials (RCT) to be the highest standard of evidence, stressing scientific validity over other evidence (Essock et al 2003). King et al (2005) argues that some patients refuse to enter into randomized trials. Therefore this leads to a bias outcome as the patients absence may weaken the findings and restrict the validity of the results. According to Bower et al (2001), there is very limited researched evidence concerning patients finding self help packages acceptable, compared with the conventional therapy treatments and medication.

Neuroleptic medication is effective; however there is still an important role for the use of psychological interventions for people with psychosis (Fowler et al, 1999). According to pinto et al (1999), Cognitive behavioural therapy has an enhanced effect when delivered along side the use of anti psychotic medication. Cognitive Behavioural Therapy (CBT) is a treatment that has been well tested in people with schizophrenia and is of proven efficiency and cost effective (National Institute for Clinical Excellence, 2002). The goal of cognitive behavioural therapy is not force the patient to agree that they have symptoms of a mental illness but to reduce the severity of distress regardless of whether the accept their diagnosis (Turkington et al, 2008). Williams (2002) argues that even though CBT is effective it is in high demand therefore accessing this resource is often limited. Senskey et al (2000), reports that CBT leads to a continual clinical improvement in schizophrenia. However findings from the Cochrane meta-analysis (cormac et al, 2002) found no evidence of an effect in the longer term. Incorporating the principles of equality and diversity and evidence base practice will enhance the road to recovery for people (NMC 2008).

The word recovery has different meanings to people; whilst the word recovery is commonly used in mental health services the true understanding of the word remains limited (National Institute for Mental Health in England 2005, (NIMHE). According to Biley (2010) recovery is a word weighed down with too much expectation and is a desire for something different from that currently available in services. It is term which has caused confusion amongst researchers as they try to differentiate the true meaning of the word.

The Department of Health (2006c) recognises that it is imperative for nurses to incorporate principles of recovery within every aspects of care. This means working collaboratively and holistically with patients towards aims and goals that are meaningful to them, and being positive about change. It is also essential to promote social inclusion for people who use mental health services, along with their carers and other relevant people. According to the NMC (2008) Mental health nurses need to be working within the recovery focus approach working alongside people to support them to live a meaningful and satisfying life as defined by them in absence or presence of their symptoms.

Recovery is a deeply personal process that is distinctive to the person. There are five key concepts that the model of recovery should encompass these are hope, personal responsibility, education, self advocacy and support. It is vital to maximise on the person’s strengths this will endeavour to shift the emphasis on the nurse being the expert (Copeland 2000). Repper &Perkins (2003), suggest that nurses need to listen to patients, who are the expertise in their mental health problems instead of focusing too much on trying to promote insight into patients. Shepherd et al (2007) recognises that recovery does not necessarily mean cure alternatively it is a journey of a person living with mental health problems to build a life for themselves beyond illness. According to Rogers et al (2007) some professionals feel a deep sense of responsibility for the welfare of their patients. Many are uncomfortable in encouraging patients to take substantial risks to reach their self determine goals. This will inevitably conflict with the recovery’s emphasis on hope and empowerment.

There are variations of tools used within the recovery model. Examples of some of these are the Wellness Recovery Action Plan (WRAP) (Copeland 2009) and the Tidal Model (Barker 2001). The WRAP has been developed by a group of people who experience mental health problems. It enables people to identify what keeps them well and use their own wellness tools to relieve difficult feelings to maintain their wellness. It is written by the individual and incorporates an action plan in the event of crisis. Key people can then be identified who can advocate for them when they do not have the capacity to do so. Support time and recovery workers were introduced as part of the government initiative The National Service Framework (NSF 1999) to support people in their recovery empowering them to lead a quality of life.

The Tidal model (Barker 2001) was the first research based model of mental health recovery originally developed by nurses with the support of people who had or were accessing mental health services. The tidal model believes that it should start from the person’s lowest point. It focuses on people who are at their most distressed so they can begin slowly to learn to manage this and identify what support they need from others. The tidal model emphasises on enabling people to tell their stories as this is where there problems first appear and is where any growth and recovery will be found.

In conclusion it is imperative that nurses incorporate the core values when delivering care to people with a psychosis or other mental health problem to ensure they provide a holistic high quality of care. This essay has focused on the key principles of the core values within mental health nursing. It has critically discussed how the core values impact on people who experience symptoms of psychosis.

As a quality leader for a health care organization create a manual for new employees to introduce the basic concepts of risk and quality management.

As a quality leader for a health care organization create a manual for new employees to introduce the basic concepts of risk and quality management.

Imagine you are a quality leader for a health care organization and have been asked to create a manual for new employees to introduce the basic concepts of risk and quality management.

Evidence Based Practice and Applied Nursing Research

Evidence Based Practice and Applied Nursing Research

(UG, C361, XAP1-0219)

 


Evidence Table


A


1.



Quantitative



A


r


t


i


c


l


e


:

Duthie, E., Favreau, B., & Ruperto, A. (2015, February 4). Quantitative and Qualitative Analysis of Medication Errors. Retrieved February 8, 2019, from https://www.ncbi.nlm.nih.gov/books/NBK20445/.

B


a


c


k


g


r


o


un


d


o


r


I


n


t


r


o


d


u


c


t


i


o


n
249 New York State hospitals implemented an experimental mandatory adverse event reporting system that examine hospital policy issues and identify useful interventions for future prevention.

R


e


v


i


e


w


o


f


t


h


e


L


i


t


e


r


a


t


u


r


e
In total, 14 articles were referenced within the publication.  The supporting material related to drug facts and comparisons, human errors, incident reporting, medication error prevention, and hospital guidelines.

M


e


t


h


o


d


o


l


o


g


y

 

An 11member panel utilized random error reports received by the New York State Department of Health from the 249 participating hospitals.

A committee of multidisciplinary professionals spent 24 months performing a quantitative analysis that examined several variables to include:

  • where in the medication administration process did the error occur?
  • what departments were involved?
  • how often did the same error occur?
  • what medications or medication class was involved?

D


a


t


a


A


n


a


l


y


s


i


s
A quantitative analysis of numeric data was used to calculate statistics regarding both fatal and non-fatal medication errors received from the 249 participating in the tracking program.  This type of methodology allows for greater objectivity when results are reviewed.  Also, for purposes of developing new hospital policies and procedures, numerical quantitative

data is viewed as credible and more reliable.


Quantitative Conclusions:



The medication error tracking received from the 249 pilot hospitals was successful in meeting the program mandates.  The data collected from fatal or near-fatal errors was instrumental in improving patient safety.  The information compiled will generate educational initiatives to address identified weaknesses.  These initiatives will provide knowledge and skills that proactively implement a safer medication administration system.


Quantitative: Protection and Considerations:

The researchers indicate the information compiled originated from each hospital’s risk management department and there was no need to obtain informed consent.  “In quantitative research, ethical standards prevent against such things as the fabrication or falsifying of data and therefore, promote the pursuit of knowledge and truth which is the primary goal of research.” (Duthie, 2015).


Quantitative: Strengths and Limitations:




The data collected provides useful and practical data to the healthcare industry in order to reduce the incidence of medication errors that cause fatal and non-fatal outcomes.  An initial lack of compliance from each reporting institute proved to be a problem with data collection.  However, the New York Patient Occurrence Reporting and Tracking System (NYPORTS) provided reeducation to the staff of each recruited hospital and cooperation was eventually achieved.  It was determined the most common pitfall of medication administration is human error.  Even with a careful, updated tracking system, a deficit in knowledge must be remedied by continuing education.


Quantitative: Evidence Application:



The expectation of this tracking program is to improve patient outcomes.  If implemented, these initiatives will provide healthcare workers the skills and knowledge to proactively prevent medication errors that result in serious harm.


Evidence Table


B


1.



Qualitative



A


r


t


i


c


l


e


:

Duthie, E., Favreau, B., & Ruperto, A. (2015, February 4). Quantitative and Qualitative Analysis of Medication Errors. Retrieved February 8, 2019, from https://www.ncbi.nlm.nih.gov/books/NBK20445/.

B


a


c


k


g


r


o


un


d/


I


n


t


r


o


d


u


c


t


i


o


n
In total, 14 articles were referenced within the publication.  The supporting material related to drug facts and comparisons, human errors, incident reporting, medication error prevention, and hospital guidelines.

R


e


v


i


e


w


o


f


t


h


e


L


i


t


e


r


a


t


u


r


e
In total, 14 articles were referenced within the publication.  The supporting material related to drug facts and comparisons, human errors, incident reporting, medication error prevention, and hospital guidelines.

D


i


s


c


uss


i


o


n


o


f


M


e


t


h


o


d


o


l


o


g


y
An 11member panel utilized random error reports received by the New York State Department of Health from the 249 participating hospitals.

A committee of multidisciplinary professionals spent 24 months performing a qualitative analysis that included findings that related to:

  • lessons learned
  • emergent themes
  • corrective counseling or education absent of punitive fixes

D


a


t


a


A


n


a


l


y


s


i


s
The research panel consisted of multidisciplinary professionals who were experts in medical qualitative analysis.  Upon receipt of the medication error reports, the panel categorized the collected information using a coding system.  Another qualitive approach is the narrative analysis. This is more subjective and allows a “point of view” approach by asking the following questions:

  • what is this about?
  • who?, what?, where?, when?
  • then what happened?
  • so what?


Qualitative Conclusions:



The narrative data used in qualitative analysis appears to be the best source for implementing initiatives that will reduce medication errors.  The data collected from fatal or near-fatal errors was instrumental in improving patient safety.  The information compiled will generate educational initiatives to address identified weaknesses.  These initiatives will provide knowledge and skills that proactively implement a safer medication administration system.


Qualitative: Protection and Considerations:



Qualitative research is centered around the “do no harm” platform.  One aspect of preventing medication errors is imploring the facility to provide staff with continuing education.  In addition, there needs to be a clear, detailed policy for disclosure of information to the patient regarding a medication error.


Qualitative: Strengths and Limitations:



The data collected provides useful and practical data to the healthcare industry in order to reduce the incidence of medication errors that cause fatal and non-fatal outcomes.  An initial lack of compliance from each reporting institute proved to be a problem with data collection.  However, the New York Patient Occurrence Reporting and Tracking System (NYPORTS) provided reeducation to the staff of each recruited hospital and cooperation was eventually achieved.  It was determined the most common pitfall of medication administration is human error.  Even with a careful, updated tracking system, a deficit in knowledge must be remedied by continuing education.


Qualitative: Evidence Application:



The expectation of this tracking program is to improve patient outcomes.  If implemented, these initiatives will provide healthcare workers the skills and knowledge to proactively prevent medication errors that result in serious harm.

 



References

  • Duthie, E., Favreau, B., & Ruperto, A. (2015, February 4). Quantitative and Qualitative Analysis of Medication Errors. Retrieved February 8, 2019, from https://www.ncbi.nlm.nih.gov/books/NBK20445/.

 

 

 

 

Examining the challenges of Clinical Leadership

A health care setting institution with advanced health technology and high calibers doesn’t mean quality nursing care can be offered, unless accompanying with effective clinical leadership. This essay has a strong focus on all aspects of clinical leadership. A case will be used to find out how should effective leadership skill be. Both internal and external factors should be analysed. The latter factors can be found out by PESTEL. Change management is helpful to develop strategies for handling the issue. In recommendations, teamwork, power, communication and presentation skills, conflict management, emotional intelligence and autocratic leadership style all are crucial to solve the issue and a clinician should equip with them. Before concluding all the discussion, training myself as a reflective practitioner is helpful to develop my future practice.

Clinical leadership- What is this?

It has various definitions. Harper (1995, p.81) defines a clinical leader as “one who possesses clinical expertise in specialty practice area and who uses interpersonal skills to enable nurses and other healthcare providers to deliver quality patient care.” More elaborately, it also involves an environment where nurses are empowered and where there is a vision for the future. Clinical leadership requires leadership skills for team building, confidence and respect of others, as well as vision and empowerment. Equally important, clinical leaders must also be good communicators. Meanwhile, Stanley (2006) suggests not only the abovementioned elements clinical leaders have to demonstrate, but also the followings- approachable and role model. Approachable means a clinical leader should be friendly and openness rather than controlling and dictatorial (Stanley, 2006). Role model means clinical leader who serves as an example, whose behaviour is emulated by other nurses (Stanley, 2006). To summarise the above elements, clinical leadership is effective if clinical leaders are expert in their field, and because they are approachable, effective communicators and empowered, are able to become a role model, motivating other nurses by matching their values and beliefs about nursing and care to their practice (Stanley, 2006).

Leadership is important in healthcare today. In Hong Kong, Hospital Authority emphasises any potential or experienced leaders should be educated and trained. Enhancing professional competencies and building up effective leadership is the top priority. In action, providing simulation skill-based training for nurses; developing new in-house specialty training programs for nurses; offering corporate scholarship for overseas training; creating full-time executive development positions; organising senior executive development program and other leadership development all are beneficial to nurture competent clinical leaders (Hospital Authority annual plan, 2010).

Case scenario

This short paragraph is going to describe a case I experienced at my area of practice. Having been a senior nurse at my workplace, I am mainly responsible for nursing administration, such as arranging vacation leave for my colleagues. One day, one of my subordinates requested annual leave during the Chinese Lunar New Year as she hasn’t been a long vacation leave during the festival for a few years. Her request was simply rejected because of compelling reason- inadequate manpower. I think it was reasonable to reject her request. However, the colleague had seemed disappointed my decision and complained this incident to my senior. It is time for me to contemplate which aspect, for example, communication and interpersonal skills or poor decision making, which I was doing wrong in this leadership issue. In short, there might be conflict issues between the subordinate and senior.

Analysis

There are many external factors which affecting the leadership issue. It is important to reveal them so as to maximize the opportunities and minimize the threats to my work environment. PESTEL is an analytical tool to help decision-maker to consider what external factors are important. Political, economic, social, technological, ethical and legal factors or PESTEL factors in short should be discovered. The following grid shows the analysis:

Grid 1: PESTEL analysis grid

P

E

S

T

E

L

e.g.

Any inequality legislation committed due to subordinate’s request being rejected

A lot of alternative nursing employment may contribute staff submitted resignation

Staff social life may be affected due to imbalance work and social time

Outdated IT equipments impede work flow and efficiency

Unfair to the subordinate or not, lack of respect as her wish is rejected

Take precaution of any changes in employees holidays policy/protocol

Having listed the key factor in each PESTEL area, elaboration will be given regarding to individual area. Political factor can be interpreted as what is happening politically in the environment in which a decision-maker operates (Mennen, 2007). A decision-maker should pay attention that any inequality ordinance may be committed, for subordinate’s request for holidays during public holidays is refused. Economic factor can be interpreted as what is happening within the economy (Mennen, 2007). A decision-maker should take notice on every decision. Careless decision may incur angry healthcare staff submitted resignation, for there are a lot of nursing vacancies offered by other clinics, hospitals and old age homes. Social factor can be interpreted as what is occurring socially in an environment in which a decision-maker operates (Mennen, 2007). Having vacation leave during special festival is a reasonable desire for all shift-based healthcare staff. A decision-maker may be in dilemma whose staff can have vacation leave as manpower is so tight. Technological factor can be interpreted as what is happening in technology which can impact what a decision-maker does (Mennen, 2007). In this regard, outdated healthcare technology can affect the leadership issue also. Inefficacy may be caused by the outdated equipment results time-consuming in a simple procedure, such as preparing a roster for frontline staff. Ethical factor can be interpreted as what is right or wrong philosophically (Mennen, 2007). A decision-maker should underscore any decided judgment should be morally acceptable, such as frontline staff’s request should be fairly arranged. Prejudice and bias should be avoided. Legal factor can be interpreted as what is happening with changes to legislation (Mennen, 2007). A decision-maker should update his/her understanding in any staff vacation leave protocol or policy in order to maintain the staff maximum benefit. To make a brief summary, PESTEL can enable an organization to anticipate future threats and take action to escape from their impact.

Change management

The term-change management is coined by Lewin (1951).Change management model is known as unfreeze, change and refreeze (Mind Tools Ltd, 2010). Change is unavoidable of something is needed to be amended. This paragraph is going to explore how the change management model can be applied in the clinical issue. Before application, force field analysis should be performed. The analysis starts from the premise that any situation is held in a stable position by a series of equal and opposite forces. Change occurs about when the forces become out of balance. The analysis is useful when a decision-maker knows where he/she wants to go but is stuck. The following shows the analysis:

Restraining forces forces

Pushing forces

Maintaining adequate manpower is the top priority

Staff discontents the holiday during the Chinese New Year

Poor mood and low work efficiency due to no holidays during the special festival

Power and discipline are paramount to uphold better patient services/benefit

Involved staff politicizes the issue (i.e. complaint the issue to management level)

Frontline staff is an important asset in caring-demand work environment

To execute change, pushing forces must be greater than restricting forces and the need for change has been recognized. In application of the Lewin (1951) model, the first step should prepare the organization to accept that change is necessary, which involves break down the existing status quo before building up a new way for the next stage (Paton & McCalman, 2008). In practical step, ensuring there is strong support from management team. Compelling message should be disseminated vacation leave during special festival is possible if manpower is enough. Maintaining stable manpower is essential to provide quality nursing care. At the same time, managerial staff should remain open to subordinates concerns and address in terms of the need to change.

The second stage is where people begin to resolve their uncertainty and look for new ways to do things. People start to believe and act in ways that support the new direction (Paton & McCalman, 2008). In practical step, effective communication and empowerment are significant. More clearly, managerial staff should prepare every staff for what is happening if staff requests annual leave during special festival. Also, explanations exactly by the managerial staff how the changes will affect every staff.

The third stage is when the change (i.e. no one is approval for vacation leave during special festival unless manpower is allowed) is taking shape and subordinates have embraced the new ways of protocol, the organization is ready to refreeze (Paton & McCalman, 2008). In practical step, the organisation should anchor the changes into the culture. Establishing feedback system is helpful to sustain the change. Having vacation leave immediately after special festival is encouraged.

Recommendations

There are six recommendations to solve the leadership issue. The concept of teamwork should be imparted into the ward practice. Nursing care is teamwork-based. The importance of teamwork should not be ignored. Teamwork in health care can be defined as a dynamic process involving two or more health care professionals with complementary backgrounds and skills, sharing common health goals and exercising collaborated physical and mental effort in assessing, planning, or evaluating client care (Agich, 1982). I have to explain her that the importance of teamwork. All colleagues need to understand how important it is for them to work smoothly together if they want to provide quality care. All colleagues must be dedicated to the whole nursing team and be willing to act unselfishly. In other words, sacrifice, in a certain extent, is necessary. To build up teamwork culture, making sure that the team goals are completely clear and understood and accepted by each frontline staff. In addition, I have to be careful with interpersonal issues. Early recognising them and dealing with them in full are highly recommended.

Power

There is a famous proverb-nothing can be done without power (Power, 1999). The appropriate use of power is important for clinical leadership, for a healthcare setting environment depends on social relationship based on power. Power (1999) defines power in terms of control or influence over the behaviour of other with or without their consent. Power can be classified as physical, position, resources, expert and intuitive. Position rather than other power should be used in the issue. Position power equals legitimate power. It means occupancy of a role entitles one to the rights of that role in the organization (Power, 1999). As a decision-maker, I have considerable right to determine something. Not approving staff with vacant leave during the special festival during the Chinese New Year is a logical and reasonable decision. Both parties’ interest (i.e. patient and ward) can be preserved.

Presentation and communication skills

Oral communication skills consistently rank near the top of competencies valued by clinical leaders. As a clinical leader, promoting positive workplace relations through conservation is highly recommended (Burnard, 1997).. In the leadership issue, I have to offer constructive criticism pertinent to the issue rather than directly rejecting her request. Think currently about what I want to say is the first step. Next, be specific in conveying core message during face-to-face communication. Clear rather than vague assertion is preferred. I do wish there is enough manpower during the special festival so you can have holiday us better than your request is banned due to inadequate manpower. On the one hand, I have to offer help and empathy her. More clearly, holiday after the special festival should be arranged immediately and understanding that the mood of no holiday during the festival.

Conflict management

Since different staff will have different viewpoints, ideas and desire, conflict is unavoidable in any group. The sources of conflict are disagreement on how things should be done, personal interest as well as tension and stress (Shortell & Kaluzny, 1997). The outcomes of conflict include polarization, low morale and regrettable behaviours produced. Therefore, conflict should be well encouraged In this regard, understanding how conflicts arise is important. Obviously, the above mentioned conflict can be categorized as personal interest (i.e. requesting on holidays during the special festival). To handle the conflict due to personal interest, compromise or negotiation is effective to settle down the incident. I have to talk with her gently as manpower is too tense, your compromise is critical. At the same time, I have to manage the issue intelligently, banning her request straightforwardly seems provoking her emotion. Rather, I have to refuse her request euphemistically. For example, your request must be approved if manpower is enough.

Emotional intelligence

Emotional intelligence is recognition of our own feelings and those of others (,). A clinical leader who accurately perceives other’s emotions can handle change better and build stronger social networks. To achieve so, three emotional intelligence skills a clinical leader should possess. The skills include social skills, motivation and self-awareness. Social skills are the ability to influence or persuade others (Pahl, 2008). Good communication skill is a typical example. Motivation is able to enjoy challenges and be passionate about work and initiate optimism (Pahl, 2008). Motivating all frontline staff to work at the special festival is a big challenge task. Self awareness is a deep understanding of one’s emotions or self-assessment in short (Pahl, 2008). Understanding my own strengths and weaknesses is helpful to deal with emotional event.

Authoritarian

Autocratic rather than laissez-faire and democratic styles should be considered. Autocratic style is an autocratic leader who is directive and makes decisions for a group. Being autocratic does not mean the leader is a dictator. Instead, the leader usually provides direction and makes decisions (Northhouse, 2010). Meanwhile, laisser-faire style is noninterference in the affairs of others and democratic style is subordinates have an equal say in the decision-making process (Northhouse, 2010). In the leadership issue, if a lot of subordinates’ requests annual leave during the special festival, inadequate manpower is guaranteed. Therefore, laissez-faire and democratic styles mustn’t be adopted because it is impossible for subordinates to freely choose the period of vacation leave. To prevent any chaos in holiday arrangement, autocratic style is the best style to be adopted.

Development of future practice

This experience should be in my heart because the experience I engaged is helpful to my future practice. Reflective practice is highly recommended. It is associated with learning from past experience, and is regarded as an important strategy for health professionals who embrace lifelong learning (Johns, 2009). Due to the ever changing context of healthcare, there is a high level of demand on healthcare professional’s expertise. Healthcare professionals could benefit from reflective practice, since the act of reflection is seen as a way of promoting the development of autonomous and qualified professionals. Engaging in reflective practice is associated with the improvement of the quality of care and stimulating professional growth. In practical step, there are several frameworks for reflection, for instance, Gibbs reflective cycle. Gibbs (1998) developed the reflective cycle in order to provide structure for reflecting on a nursing situation. The cycle involves six phases. The first phase is to describe what happen (i.e. the case scenario). The second phase is to think and feel about the scenario (i.e. unwisely to handle the issue). The third phase is to evaluate what was good and bad about the experience (i.e. adequate manpower can be maintained but the involved subordinate become angry). The fourth phase is to analyse what sense can I make of the issue (i.e. managing conflict of personal interest intelligently). The fifth phase is to think what else could I have done (i.e. managing conflict tactically). The final phase is to prepare contingency plan (i.e. if it arose again, what would I do).

Conclusion

So far, all aspects of clinical leadership have been covered. To solve the issue due to personal interest, negotiation with involved staff, wisely-used conflict management skills, fully utilizing position power and compelling presentation skills all are constructive to the issue. Before settling down the issue, both PESTEL analysis and change management should be engaged. The strengths of the above are to discover any threats as soon as possible and implement related changes immediately. Successful settling down the issue doesn’t mean a clinical leader demonstrates effective clinical leadership. As clinical leadership is a persistent phenomena performed by a clinical leader, reflective skill a clinical leader should have so as to enhance clinical leadership in an advanced level. (Words: 2711)

A female client with cancer is receiving chemotherapy and develops thrombocytopenia

A female client with cancer is receiving chemotherapy and develops thrombocytopenia.

A female client with cancer is receiving chemotherapy and develops thrombocytopenia. The nurse identifies which intervention as the highest priority in the nursing plan of care?
A female client with cancer is receiving chemotherapy and develops thrombocytopenia. The nurse identifies which intervention as the highest priority in the nursing plan of care?

A. Monitoring temperature
B. Ambulation three times daily
C. Monitoring the platelet count
D. Monitoring for pathological fractures

Identify the resource you would recommend to patients for evaluating online health information and why it would be beneficial.

Identify the resource you would recommend to patients for evaluating online health information and why it would be beneficial.

 

a)Post your assessment of the nurses role in improving the health literacy of patients.
b) identify the resource you would recommend to patients for evaluating online health information and why it would be beneficial.
c)Describe additional strategies for assisting patients in becoming informed consumers of online health information.
In order to effectively manage their own health, individuals need to have competencies in two areasbasic literacy and basic health literacy. What is the difference? Basic literacy refers to the ability to read, even simple language. Health literacy is defined as, the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions (National Coalition for Literacy, 2009). Unfortunately, according to a Department of Education report on health literacy, only 12% of adults aged 16 and older are considered to have a proficient level of health literacy (U.S. Department of Education, 2006). Acquiring health literacy skills has become more complicated with the explosion of online health information, some credible and some misleading.
In this Discussion, you focus on how to help individuals find credible information on the Internet and develop strategies nurses can use to increase the health literacy of their patients.
To prepare:
Think about the nurses role in improving the health literacy of patients.
Consider the many ways patients access health information, including blogs, social media, patient portals, websites, etc.
Reflect on experiences you have had with patients who self-diagnose using online medical sources.
Using the Internet, the Walden Library, or other trustworthy sources, identify a resource that you could introduce to patients to help them evaluate the credibility of health information found online.
What are some strategies you could employ to improve the health literacy of patients?
Resources
McGonigle, D., & Mastrian, K. G. (2015). Nursing informatics and the foundation of knowledge (3rd ed.). Burlington, MA: Jones and Bartlett Learning.
Chapter 17, Supporting Consumer Information and Education Needs
This chapter explores health literacy and e-health. The chapter examines a multitude of technology-based approaches to consumer health education.

Chapter 18, Using Informatics to Promote Community/Population Health
In this chapter, the authors supply an overview of community and population health informatics. The authors explore a variety of informatics tools used to promote community and population health.

Chapter 16, Informatics Tools to Promote Patient Safety and Clinical Outcomes
The authors of this chapter present strategies for developing a culture of safety using informatics tools. In addition, the chapter analyzes how human factors contribute to errors.
Health literacy: How do your patients rate? (2011). Urology Times, 39(9), 32.
Retrieved from the Walden Library databases.

The authors of this article define health literacy and emphasize its poor rates in the United States. Additionally, the authors recommend numerous websites that offer patient education materials.
Huff, C. (2011). Does your patient really understand? H&HN, 85(10), 34.
Retrieved from the Walden Library databases.

This article defines hospital literacy and highlights the barriers that prevent it from increasing. It also emphasizes the difficulties created by language and financial costs.
The Harvard School of Public Health. (2010). Health literacy studies. Retrieved from https://www.hsph.harvard.edu/healthliteracy

This website provides information and resources related to health literacy. The site details the field of health literacy and also includes research findings, policy reports and initiatives, and practice strategies and tools.
Office of Disease Prevention and Health Promotion (n.d.). Health literacy online. Retrieved June 19, 2012, from https://www.health.gov/healthliteracyonline/

This webpage supplies a guide to writing and designing health websites aimed at increasing health literacy. The guide presents six strategies that should be used when developing health websites.
U.S. Department of Health and Human Services. (n.d.a). Quick guide to health literacy. Retrieved June 19, 2012, from https://www.health.gov/communication/literacy/quickguide/Quickguide.pdf

This article contains an overview of key health literacy concepts and techniques for improving health literacy. The article also includes examples of health literacy best practices and suggestions for improving health literacy.
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History and assessment of massage therapy

Massage therapy is the manipulation of the soft tissue on the body by a practitioner through the movement of their hands and arms as well as advanced techniques. Massage has been used to help people relax as well as a way to help treat minor ailments as a complement to other medication or treatment. As A Whirlwind Tour through the entire History of Massage webpage states ‘Massage is a universal instinct. From the day they descended from the trees, humans have known that it helps to rub a sore limb and that to touch is beneficial.’ So since then we have used and developed the skills and techniques through the years into the massage routines we see and use today.

History of Massage;

Throughout ancient history many different countries have been using massage and developing their skills as well as passing these down through the years. They have been borrowed, stolen and shared through different times as well as different places geographically around the world, many of the different types of massages resemble each other as techniques have been copied, borrowed and shared.

Pre-historic people used to practise some forms of therapeutic touch or massage as there has been evidence to suggest that they used to massage their muscles and rub herbs and oils onto their bodies to help with healing or to protect as this has been found in caveman paintings and drawings showing the giving and receiving of massage.

After then the next stage that has been recorded in history to show the major use of massage where the Chinese in around 3000BC in a book called ‘Con Fou of the Tao-Tse.’ As mentioned in the eBook History of Massage, Therapies & Rules in China ‘for years, blind people where the main masseurs.’ According to A Whirlwind Tour Through the entire history of Massage ‘Chinese writing dates from around 1400BC, near the start of the Shang dynasty, and it from around this time that we can reliably date massage.’ It was in China that the first exam in massage was sat about fifteen hundred years later as an addition to the occult studies schools. Around the same times as China the Egyptians also used massage and this has been depicted in tomb paintings of individuals being ‘Kneaded’ by others. The Japanese’s received their knowledge from China through the study of Buddhism and soon customised the techniques which became known as anma, which later became Japanese Shiatsu. According to The history of Massage: Learn How Massage Dates Back over 5,000 Years Ago ‘The primary goal of Shiatsu is to raise the energy level in the patient. In turn, this increased energy level regulates and fortifies the functioning of the organs and stimulates natural resistance to illnesses.’ The practitioners use a variety of techniques to pressure points on the body to balance the energies and work without needles or other equipment to do so.

However, some sources believe India was practicing massage before the Egyptians and the Chinese while others believe they might have acquired it from China a little later so the dates of when India first started to use any forms of massage range from around 3000BC to between 1.800-500BC.

‘Massage in India is referred to in ancient Hindu books such as ‘Ayurveda’ (Art of Life) which was written around 1800BC. It describes how movements such as shampooing and rubbing were used to relieve tiredness, increase energy levels and improve general health.’ Francesca Gould in Body Massage for Holistic Therapists (2004).

After this stage in history the next step in the time line is around 2000BC when the Greeks and Romans first started to use massage in the early foundations of their civilisations. The ancient Greeks used the knowledge from the Egyptians massage techniques, and it was given to the athletes’, women and soldiers as described in History of Massage, Therapies & Rules. The Greeks wrote many books on massage including some written by Homer, Aesculapius, Herodotus and Hippocrates who was the ‘Father ‘of Medicine. It was the Greeks who used to rub up the body towards the heart to help the venous and lymph in that direction, they also used this technique to move sickness towards the centre of the body to where is can be expelled with the waste materials.

The Romans however used massage as more of an indulgence than as a medical therapy; it was saved for those who could pay for it. The Romans received massage from the Greeks and enjoyed bathing before a full body massage and it was said that even Julius Caesar was pinched every day. The Roman gladiators were vigorously massaged before fights to make sure their muscles where warmed up and supple. Galen was the main figure in Rome for massage but he was actually Greek, according to A Whirlwind Tour through the History of Massage he lived from 130AD to 201AD and he acquired his knowledge of anatomy and physiology through working with the gladiators. Massage then was used as an alternative for exercise to help relive their excessive eating and drinking.

Massage was used throughout the different tribes in North America before the Europeans arrived, some tribes would massage/rub down their warriors before and after battle or rub ointments into ailing joints or muscles. Massage has also been seen through a variety of different countries through history including those such as Persia, Kurdistan, Thailand, Tibet, Indonesia and Hawaii.

The most recent history of massage can be seen is western civilisation. The earliest record was written by Ambroise Pare (1510-1590) but he was ridiculed for his publication. However by the time Henrik Ling (1776-1839) became the father of modern western massage it had become less of a ridicule. As the History of Massage, Therapies & rules tell us Henrik Ling once put. “We ought not to consider the organs of the body as the lifeless forms of a mechanical mass,” he wrote, “but as the living, active instruments of the soul.” And through this he finally developed the system known as Swedish massage.

Massage has now moved back towards the old holistic attributes instead of the physiological attributes so we are back to seeing massage in the same way as the ancient Chinese, Egyptians and Greeks once saw the therapy. As reported by The Massage Bible, ‘during the first World War injured soldiers were treated with massage, while the Californian bodywork movement in the 1960s combined massage with personal growth.’ There are many different kinds of massage practiced today all over the world and many of them can be received by almost anyone unless they have a specific reason that it cannot be preformed. There are a few different people who have been in the forefront of massage in modern history and those are Cornelius E. Who is the ‘Father’ of massage in the USA, David Palmer, the ‘Father’ of chair massage, Dr Tiffany Fields, the ‘Mother’ of massage research and Jack Meagher the ‘Father’ of sports massage. In figure I. In the appendices is a time line of the history of massage along with the creation and history of other therapies this has been take from the eBook History of Massage, Therapies & Rules.

Massage Principles and Holistic Experience:

To decide if massage is a holistic therapy first of all we need to know what holistic means and according to thefreedictionary.com Holistic means ‘Concerned with wholes rather than analysis or separation into parts.’ And with this definition we shall determine whether or not massage is a holistic experience.

A massage whether it is a Swedish, Shiatsu or any other form of massage moves across the whole surface of the skin missing only a few vital places which are left for either health and safety reasons or due to the intimacy of the area. Most massages that even just incorporate one certain area such as an Indian head massage or even reflexology they all use different points of that area to correspond with different areas or energies upon the body. With different energies running throughout in specific channels which move around the entire body, when a massage is preformed to the whole body or even just a small portion of the body such as the hands, feet or head all the energies are involved which in turn incorporates the body as a whole. With this in mind a massage can be believed to be Holistic as this matches with the definition of holistic in taking the body as a whole instead of a separation of its individual parts.

There is only one reason as to not treat a certain part of the body and that is due to a contra-indication such as pregnancy where you would not touch or massage the abdominal area or is say someone had a fungal infection upon their feet you would not massage their feet and would move onto the next step of the massage itself. These contra-indications could be on a temporary basis or they could be permanent and therefore this client would not be able to receive a treatment. There are some contra-indications such as cancer, epilepsy and a few others which would need a doctor’s approval before a treatment could be carried out upon the client for insurance reasons. For example for epilepsy if you do not know the trigger for a seizure and you had not received a doctors approval for the treatment and the client unfortunately had a seizure upon your table then the client might decide to sue the practitioner for causing this, this is why doctors approval is sought.

Due to the Health and Safety at work act 1974 all employers and employees must maintain a high standard of health and safety in the work place as described in F. Gould’s Body Massage for Holistic Therapists.

‘Employers are responsible for the health and safety of anyone who enters their premises. If an employer has more than five employees, the work place must have a health and safety policy, of which all staff must be aware.’

There are many different procedures in the work place that all employees must adhere to such as the first aid and fire procedures, all employees should know where the first aid kits and fire extinguishers/ exits are located within the building for the safely of themselves and the clients, It is advisable however, that all practitioners are first aid qualified themselves in the event of an emergency. From the clients point of view the practitioner should know these things as well as have a basic understanding of personal hygiene in the sense of washing their hands properly, being of a clean and presentable appearance and be dressed appropriately for the treatment. This is due to the intimate nature of the massage with the close skin to skin contact as strong smelling perfumes or strong body odour can be very unpleasant for the client. A general knowledge of health and safety is beneficial for the example to clean up spillages as and when they happen as to avoid trips, slips and falls of either the client or yourself. A good general idea of protecting your equipment is ideal as oils and creams can become a hazard if left un-cleaned from the treatment table as this could cause a slip or the degrading of your equipment such as the vinyl of the table tops.

For insurance purposes the practitioner must ensure that they do not perform a massage while they are unwell or when the client is contagious due to the spread of infection and should always wear gloves if they have any open areas upon their hands. This is for their own protection and that of the client as to not pass anything between them or onto any other client from the previous client. However it is also important to know if the client is well enough to receive the treatment, for this the practitioner must refer to the contraindication lists to see whether or not the client is acceptable to treat. The client should also be aware that at any point the practitioner is legally allowed to refuse treatment for withholding information or for unacceptable behaviour. The practitioner must also get the permission off the client at all times before a treatment if they can touch the client themselves, and they must ensure the client understands this and what is going to happen during the treatment for insurance purposes for the protection of both the client and practitioner.

Personal safety for the practitioner is also important; these include the correct posture and the compression of the wrists. If either of these are incorrect then the practitioner later in their career could cause themselves more pain due to repetitive strain on the joints and could cause more damage if continued. To help prevent this the right table height should be selected for the practitioner as well as the correct foot wear to help with posture, also the right hand movements should be followed to help prevent the compression of the wrists. The most important piece of safety a practitioner should adhere to is their own safety when working with a client on their own such as a residential call or even in their own rooms at their treatment centre. If doing a residential call then the practitioner should only really perform these on clients that already know, they have a personal phone number for and they should always make sure someone knows where they are at which times and check in after the appointment with either a family member or work colleague to show they are safe. If they get a new client after a residential call they should always follow the rules of asking for the residential phone number and insist upon phoning the day before the treatment to see if they still wish to receive the treatment.

Making the treatment of a client a positive experience is one of the most important parts of making a massage holistic, the practitioner should look after their clients making sure they are comfortable with what is going on whether they are new or long term clients. To be a massage practitioner you should have excellent customer service skills, client care should be the most important thing to remember and should always be used every day with every client, the client should believe that the practitioner cares. The practitioner should always consult with the client and devise a treatment plan to suite the clients and stick to this plan unless anything changes in the circumstances with the client as well as receiving permission from the client for the practitioner to touch them during the treatment. During the treatment the discussion should be at a comfortable level for the client but also low enough for the client to relax and enjoy the treatment. After care should always be adhered to and offered to the client with a small encouragement of lifestyle changes if needed for the client’s needs.

Effects of Massage including the Physiological and psychological effects upon the client:

Massage even though it is a holistic experience has been seen to have an effect of other areas of the human body and not just as a way to relax; a massage has been seen to show that it has both physiological and psychological effect upon the clients. Physiological effects are those which are shown upon the body itself and its function whereas psychological effects are those which manifest themselves in the mind and the emotions of the client. There are many different outcomes which could manifest for both on the anatomy and the body systems. In two different clinical trials that have been preformed independently of each other there is a show of the two different effects received after a massage treatment, one for the Physiological effects and one for the psychological effects.

In the first trial the objective was to see if the early intervention with massage in children with Down syndrome would help with the motor skills and muscle tone. So parents with children suffering from Down syndrome where asked to attend one of two early intervention classes, one class was a body massage session and the other a reading session after a base line had been assessed upon their severity of the syndrome, some children were not used if sever mobility where involved or they had emotional problems as this might interfere with the trial.

Twelve of the children were assigned to the massage sessions and eleven to the control reading session, so in overall there where twenty one children involved in this trial. Each session was scheduled for the same times each week and specific times of the day for both classes, and each session was on an individual basis, the sessions lasted for half an hour each, twice a week for two months, while the reading session was conducted the same way with the therapist holding the child while reading for the half an hour.

This was the treatment that the children received in the following sequence:

‘The 30-minute massage therapy session started with the child lying on a small mat

on the floor. The therapist conducted the following sequence three times with the

child in a supine position: Legs and feet-(a) while forming hands like a letter ‘C’ and

wrapping the fingers around the child’s leg, long, milking and twisting strokes from

the thigh to the ankles; (b) massaging foot by gliding thumbs across bottom of foot

followed by squeezing and tugging each toe; (c) massaging across top of foot by gliding thumbs from ankle to toes; (d) flexing and extending the foot; (e) massaging from ankle to foot and back to ankle; (f) stroking from the ankle up towards the thigh; and (g) back and forth rolling movements (as if making a rope from dough) from the

ankle to the thigh. Stomach-(a) slow, circular, rubbing movements to stomach area

with one hand; (b) using the palms, hand over hand down the stomach in a paddlewheel fashion; (c) starting with thumbs together at the umbilicus, stroking horizontally to sides of body and then twice above and twice below the umbilicus; (d) using fingertips and starting below the umbilicus on the child’s right side, small circular upward movements until even with the umbilicus, then continuing across to the left side, and then down on the left side to below the umbilicus; (e) with one hand

following the other, short upward stroking from right side below the umbilicus, then

Massage and Down syndrome 401 across the umbilicus to the left side of the body, and then down on the left side to below the umbilicus; and (f) cupping or holding sides of knees, bending both knees simultaneously towards the stomach and holding for three to five seconds. Chest-(a) with palms of hands on child’s sternum, stroking outward across chest; (b) starting at sternum, stroking upwards and over tops of shoulders and down the sides of the ribs; and (c) starting at the right thigh, stroking diagonally through the chest to the opposite shoulder and back down to the same thigh; repeat starting at the left thigh; Arms and hands-same as legs and feet (i.e. replace ‘legs’ with ‘arms’ and ‘feet’ with ‘hands’). Face-(a) making small circles to entire scalp (as if shampooing hair); (b) with flats of thumbs together on midline of forehead, stroking outward towards the temples; (c) stroking gently over the eyes and brows; (d) starting at the bridge of the nose, stroking across the cheekbones to the ears; and (e) making circular movements under the chin, around the jaw line, around the ears, to the back of the neck and the rest of the scalp. The following sequences were done after placing the children on their stomach (in a prone position). Back-applying oil to the hands: (a) starting at the top of the spine, alternating hand strokes across the back working down towards the tail bone (never

pressing the spine) and reaching over to include the sides; (b) hand over hand movements from upper back to hips with flats of hands and then continuing to feet; (c) using circular motion with fingertips, from neck to hips stroking over the long muscles next to the spine and retracing on the other side of the spine; (d) making circular strokes with the palm of the hand to rub the tops of the shoulders; and (e) ending with long gliding strokes from the neck to the feet.’ As was described in the journal Children with Down syndrome improved in motor functioning and muscle tone following massage therapy (2006).

The trial was held at the children’s early intervention pre-school centres, while the test was run by the university of Miami school of medicine. The results of this trial show that there was a greater gain for the results of the children who where massaged in their sessions than to those who where read too. The improvements were shown in the gross motor skills and fine motor skills development of the children as well as a marginal effect in their language development. This then showed that through the early intervention with massage it could help children with Down syndrome enhance their motor development at a faster rate than if they were left to mature in their own way.

These results help to show that massage can have a physiological effect upon the body in helping to produce and enhance muscle tone. However, there is the argument that another control group could have been added into the trial to help show whether this is successful or not is a control group that uses light stokes instead of a pressure massage to help with the ethical problems of withholding the intervention from those in the reading session. This was all shown in the clinical trial journal of Children with Down syndrome improved in motor functioning and muscle tone following massage therapy (2006) which is located in the appendices.

The second trial is to determine whether or not massage can have a psychological effect on the client and for this the trial was preformed for the Association of Paediatric Haematology/Oncology Nurses (2009). The aim of this trial was to reduce symptoms of children with cancer and to reduce the anxiety of their parents.

‘Children with cancer, ages 1 to 18 years, received at least 2 identical cycles of

Chemotherapy, and one parent, participated in the 2- period crossover design in which 4 weekly massage sessions alternated with 4 weekly quiet-time control

Sessions.’ As described in the article Massage Therapy for Children with Cancer (2009).

To determine if the massage was helping to relieve the psychological symptoms of anxiety in the parents and the symptoms of the children while the trial was progressing they measured everyone’s heart and respiratory rates, blood pressure, and salivary cortisol level as well as their pain, nausea, anxiety, and fatigue levels.

According to the results of this trial the massage was more effective in reducing heart rate than quiet time in the children, the anxiety in the children aged fourteen and older and the anxiety in the adults. The clients all commented upon how the massage rather than the quiet time helped with their anxiety and helped them feel better. So due to their result it is feasible to massage children with cancer and their parents to help relieve their anxiety. Therefore this result helps to show that massage to the body can have a psychological effect upon the client in this sense it has reduced the anxiety of the both the children and the parents although in the younger babies the results did vary a little more than the other ages, but the results of the older children and the adults help to prove that just a massage on its own can have a psychological effect upon the human body. The trial that this assessment was based upon is located in the appendices as clinical trial 2.

So both of these trials show that massage can had a successful outcome on the physiological and psychological effects portrayed on the body, they both proved that through a short massage the body can manifest its effects through muscle tone or motor function progression as well as to reduce anxiety in both children and adults. Neither of these two trials have a negative out come and therefore both are a success but there shall be a few trials where massage has not appeared to be successful at all or shows that it is a little less successful than anticipated, these however are normal and show both sides to an ongoing argument about whether massage is actually good for the body, mind and spirit on a whole or if it just theoretically works on the body.

Causes of Stress and Their Impacts

Causes of Stress and Their Impacts


Causes of Stress and Their Impacts

Stress has many different causes as well as negative impacts that are associated with it. The effects that stress has on police officers are numerous. When thinking about the word “Stress” and all of the many different definitions that people apply it to, it becomes clear that it is difficult to measure due to the lack of consensus on what the true definition of the word should be (American Institute of Stress, 2017).  Stress is by no means permanent, and it can be managed or reduced through a number of effective methods (Hansen, n.d.). When considering stress, most people associate it with bad feelings and negative outcomes of situations. It is important to note that not all stress is necessarily bad. Stress is caused by a reaction to an encountered situation that often poses risk. This situation is comprised external and internal elements and the interaction of the two. Distress is the stress encountered in daily life that has negative connotations such as a break up, punishment, getting hurt or injured, bad feelings, financial issues, and problems at work (American Institute of Stress, 2017). These reactions can create an assortment of different effects; both mentally and physically. Experiencing stress can affect your mood, create feelings of anxiety, make one restlessness, create a lack of motivation/focus, feeling overwhelmed, irritability/anger, and or sadness/depression (Mayo Clinic, 2016).

When examining the many major causes of stress for law enforcement officers; try to keep in mind that stress has many different effects on people. What can cause one-person distress may not be a source of stress for the next person. It is a well-known fact that individuals who work in law enforcement or any other emergency service experience a variety of stress intense situations and are required to perform immediate actions in order to gain control of the situation and sometimes force individuals to endure traumatic events that are unique to their job (Regehr, LeBlanc, Barath, Balch, & Birze, 2013). Police officers generally have to work long hours that constantly change, and when combined with the officer’s having to work in ever-changing environments, it is no wonder that law enforcement personnel are under a large amount of mental and physical stress (National Institute of Justice, 2012). The stressors can be intensified by both personel and professional situations that can be carried into one another. Stress from police work can be caused by several things. Officers must endure shift changes, conflicts on the job such as choosing how to enforce the law, the constant threat on their lives, and a long list of other things. A police officer must be able to control their emotions even when provoked and are constantly being exposed to gruesome situations (University of Minnesota, n.d.). Any one of these pressures alone is enough to overly stress a common person, but an officer must endure all of them and still function at the highest level.

The stress that stems from police work can cause some serious health problems if not dealt with in a healthy way. Chronic stress will lead to high blood pressure as well as heart issues, insomnia, and other sleeping preventatives. Stress can also lead to mental illness such as post-traumatic stress disorder (PTSD) and lead to suicide due to the increase of destructive stress hormones. University at Buffalo researchers have studied the effects of stress on police officers for a decade and have found these results (Baker, 2008). When an individual holds on to stress rather than deal with it in a healthy way, the stress can cause the person to experience anxiety, depression or post-traumatic stress disorder (PTSD) (National Institute of Justice, 2012). A majority of the stress stems from a constant change in sleep schedule and shift schedule. This combination of stress and change of schedule can lead to being exhausted and fatigued. Being tired can be detrimental to the health of law enforcement both mentally and physically. Exhaustion has many side effects on law enforcement, most of which are mental, and include frequent mood swings, impaired judgment, a decrease in adaptability, and heightening the sense that a threat is imminent. Fatigue can also increase anxiety and depression as well as increase the chance that an officer develops mental illnesses such as PTSD or bipolar disorders (National Institute of Justice, 2012). Being exhausted can bring just as much harm to the law enforcement officer’s physical health by leading to high blood pressure, heart disease, and eventually heart failure if left untreated. Sleep disorders have become common in police officers due to their frequently changing schedules, both work and sleep, due to overtime and overnight shifts (National Institute of Justice, 2012).

Sleep disorders generally are a sign of a person being unhealthy and can cause an officer to lower their performance capabilities which in turn make unsafe outcomes more likely to occur. Law enforcement officers are twice as likely to have a sleep disorder and a study shows that many of these officers remain undiagnosed and untreated (National Institute of Justice, 2012). The sleep disorder that is most prevalent amongst law enforcement officers is sleep apnea quickly followed by insomnia. If insomnia is left untreated it could create even more health issues ahead of time.

When law enforcement personnel become critically stressed due to all the present stressors, both personal and professional, it could play a large role in their performance in the field and put many lives at risk. Those serving their community in a branch of law enforcement are likely to have the mindset that accepts over exhaustion and stress as part of the job. With this state of mind, the signs and symptoms of both stress and being overly tired are ignored until a dangerous and serious incident brings it to light. A study on police officer exhaustion showed the following terrifying facts about law enforcement personnel being stressed and tired. Fatigued officers use more of their sick days and have trouble managing healthy relationships with other. Officers will have time management issues and will tend to show up to work late more frequently. Exhausted officers are more likely to make mistakes and errors on paperwork and will recieve higher rates of complaints from citizens for careless acts and acts of misconduct. Due to the frequent rotation of shifts, officers are more likely to fall asleep while on duty and have issues testifying in court regardless of how prepared they are. Police officers will have issues communicating with their supervisors and will have stressed relationships with leadership. Worst of all, officers who are fatigued have a higher chance of hurting themselves or others due to lack of focus and missing danger signs. Officers are also more likely to retire earlier due to burnout. (Bond, 2014).

Individuals serving in the policing community, will seldom talk about these sources of stress due to fear of appearing weak and potentially creating more issues along the way. Police officers are committing suicide and suffering with their stress and traumas alone and in silence because of a fear based on a stigma against showing weakness and what their department may do (Olson & Wasilewski, 2016). Law enforcement personnel face stress on their own due to the stigma that they may receive for appearing weak due to severe and chronic stress. Law enforcement personnel may fear that their career or promotion could be in jeopardy if they decide to receive help for stress related problems. That is where the cycle continues to keep officers constantly stressed. Good leadership is important to any organization and is critical to combat this stigma and end the cycle of chronic stress.

There are preventable stressors that law enforcement personnel have to endure such as scarce amounts of training, excessive amounts of paperwork, and the absence of constant rewards for great job performance (University of Minnesota, n.d.). It is critical for the leadership of the department to acknowledge and manage their law enforcement personnel correctly by creating a work to rest ratio that does not risk the overall welfare of the agency or its officers. Surrounding the department with exceptional people will create a work environment that inspires officers to be motivated and dedicated to the goals of the department.

Police officers also receive stressors from the internal organization of law enforcement. Confusion of roles, conflict with roles given and who completes which role, lacking support from supervisors, few opportunities for promotion, as well as a lack of unity with coworkers all cause stress for officers (Hassell, Archbold, & Stichman, 2011).  Departments that have bad leadership traits and strict rules and policies could also add to the stress that law enforcement personnel face due to the constant feeling of being under a microscope. One of the most common agency stressors can be leadership and how department leaders run the agency altogether. By taking an already stress intense job and adding any unnecessary stress along with what is already associated will bring down the morale and raise the anxiety level higher than what is appropriate. With so many expectations for perfection with so few rewards and opportunities, police officers often feel as if they have less rights than the suspects that they apprehend (University of Minnesota, n.d.). The addition of stress from work may cause police officers to have problems in their personal lives as well. These problems include a range of things including family, financial, or even health issues. When left alone and not dealt with in a healthy way, stress only creates more stress. By increasing the amount of money going to more impoverished sectors the workload will shrink thus creating a more enjoyable place to work and in turn lowering stress level in police officers (Hansen, n.d.).

When a stressful situation arises, individuals will find that their body and mind become flooded with chemicals that begin the fight or flight response. The fight or flight response is a natural response meant to help individuals to survive. However, this response at times can become unhealthy. Any activities that an individual can partake in that will help distract them from their unhealthy thinking habits and gives them a source of joy is a great stress relieving technique. The fight or flight response is usually where problems come into play. Law enforcement personnel are not always properly trained or educated on how to deal with and combat large amounts of stress. Due to their lack of training, many are unaware of how to deal with these stressful events in a healthy way which can create more problems in their work and personal lives. By receiving proper training and being educated on how to recognize the damaging effects of stress, a police officer can adapt and overcome stress by turning distress into eustress. Law enforcement personnel and leadership can use this information as tool to motivate other each other with. All in all, sources of stress in life are all about one’s perception of the stress and how their body and mind interpret it.

People often will rely on alcohol or some other substance to help them deal with all the stress affecting them. Making a habit of this dangerous behavior will only create more destructive problems in the long run. Abusing alcohol or other substances to manage stress is a very dangerous and unhealthy way to deal with encountered stressors. Along with substance abuse, other dangerous coping mechanisms include smoking, gambling or just doing nothing to deal with the stress. Using these mechanisms can possibly create more problems in both work and personal areas in life. Processing stress in an unhealthy way and ignoring it rather than dealing with it appropriately will only cause more issues down the road which only makes the detrimental behavior worse thus creating a destructive cycle. At times, people will only be able to see the bad in life and lose sight of the good. This dangerous mindset will only create a more destructive process if an officer is not properly trained or educated on ways to deal with the stress in a healthy way. There are no definite answers to determine what outcome stress could play on law enforcement officers. However, the fact of the matter is that every officer is different from the other and every officer will handle the stress put on them differently. Research has proven that suicide rates in law enforcement are higher than most othe professions along with the divorce rate for police officers (University of Minnesota, n.d).

​​ Life is full of stress and there is no avoiding it no matter if its eustress or distress. When it comes down to it, what really matters is how one is able to perceive the stress, so they can deal with it appropriately. The way we perceive things will ultimately determine how well we work under stressful situations.  Law enforcement personnel will always undergo more stress than the typical citizen.  However, with proper training and education, officers can and will be prepared for these situations and will be able to find healthy ways to cope and manage their stress. It is important to not lose sight of the good when it starts to feel like there is nothing but bad things happening.


References

Polycyclic Aromatic Hydrocarbons Causing Breast Cancer


Abstract

Within the following report various different studies will be analysed to assess whether Polycyclic Aromatic Hydrocarbons e.g. Benzo[a]pyrene cause Breast Cancer. PAHs are ubiquitous environmental pollutants formed during the incomplete combustion of organic materials. PAHs contain carcinogenic properties and can exert their effects on humans by ingestion, inhalation and adsorption. Although the exact etiology of breast cancer is unknown, various case-control studies have been carried out that prove a direct correlation between areas with high levels of PAH concentration and the incidence of breast cancer. It’s also been shown that there was a higher level of BaP-DNA adducts in cancer patients than controls suggesting they’ve a role to play in the implication of the disease. It has also been seen that smoking causes human bronchial cells to produce stress-induced unregulated cRNA transcripts. These transcripts can also be seen in breast cancer cell lines, therefore suggesting that smoking can up regulate ncRNAs in breast cancer. Several other rodent in-vitro and in-vivo studies have been done to show how PAHs may implicate breast cancer. However not all are directly relevant to human subjects as humans would not be exposed to such high concentrations of exposure, or exposure at regular intervals. Therefore, further studies must be done to confirm if PAHs directly implicate breast cancer.


Introduction

Polycyclic Aromatic Hydrocarbons (PAHs), are a hydrocarbon – which is an organic compound comprised of two or more fused benzene rings arranged in various different configurations. (Kim et al. 2013)


Figure 1:This figure shows the structure of common PAHs found in the environment.

(Kim et al. 2013)

PAHs are uncharged nonpolar molecules found in coal and tar, but also they’re ubiquitous environmental pollutants and are formed during incomplete combustion of organic materials. (Abdel-Shafy and Mansour 2016)

Many PAHs contain mutagenic toxic and carcinogenic properties. PAH’s were one of the first atmospheric pollutants designated as a suspected carcinogen. Although the health effects  of different PAHs differ, they’re noted to be of great concern due to their highly adverse and extreme health effects on humans. (Abdel-Shafy and Mansour 2016)

Governmental Bodies such as the European Commission, NIOSH and the US EPA are monitoring conditions, and enforcing legislation around PAHs in air soil and water. For example the

European Commission

has restricted concentrations of some specific carcinogenic PAHs in consumer products that contact the skin or mouth. A PAH which is of concern that I will be discussing throughout is benzo(a)preyene. (Kim et al. 2013)

Benzo(a)preyene (BaP), with the chemical structure C20H12, is a polycyclic aromatic hydrocarbon which is found ubiquitous in nature, coal and tar. This specific PAH is found in smoked and grilled meats, making it a PAH of particular concern for humans. It is also classified as a group 1 carcinogen by the IARC. (Kim et al. 2013)

 




Figure 2: This figure shows the molecular structure of Benzopyrene (BaP) this is the most common PAH and is an ultimate carcinogen.

(Lee and Shim 2007)

There is also a lot of studies and research suggesting that Benzo(a)preyene, along with other PAHs has a direct effect on the incidence of Breast Cancer.               PAHs are a severe Endocrine Disrupters (EDs), which therefore can potentially cause negative hormone responses, resulting in Breast Cancer. (Kim et al. 2013)

Within my report I will be discussing:

  1. How PAHs were originally implicated in Breast Cancer
  2. The mechanism of exposure of PAHs
  3. Cohort and case control studies which have been used to implicate PAHs in Breast Cancer.
  4. The likely mechanism in which PAHs exerts their effect
  5. How the toxicants effects may be modified by interaction with other agents or how it reacts with the human genome to produce differing consequences for different genotypes.
  1. How PAHs were originally implicated in Breast Cancer

The exact etiology of Breast Cancer is unknown. There are of course a number of risk factors for the implication of breast cancer such as age, weight, genetics, race, smoking, exposure to radiation and diet.(Kim et al. 2013) Many carcinogens have been identified that are produced as a consequence of industrial activities, and traffic emissions.(Abdel-Shafy and Mansour 2016) And as stated, many carcinogens are speculated to implicate breast cancer such as BaP. As of yet there is no direct evidence to fully prove that PAHs of any kind can breast cancer.

However originally, it was Morris and Seifter in 1992 that suggested that the PAH emissions and the incidence of breast cancer in women were linked. The geographic locations of breast cancer cases, and also locations of high hydrocarbon residue levels were plotted. It was proven that these locations coincide. Therefore originally suggesting that PAHs implicate Breast cancer.(Morris and Seifter 1992)

  • The goal of this paper was to access the role of aromatic hydrocarbons in the genesis of breast cancer. It was previously known that epidemiological markers of breast cancer can include endocrine related phenomena, and the exposure of the breast to X-Radiation. However, polycyclic aromatic hydrocarbons had not yet been proven to be implicated in human mammary carcinogens. Upon exploration of the role of breast tissue, it was seen that the breasts are particularly susceptible to aromatic carcinogenesis. Since the breasts are largely composed of fat, PAHs can be harboured easily within the tissue. These hydrocarbons are stored and metabolised into carcinogenic metabolites. Ductal cells then become target cells for carcinogenesis as they concentrate the metabolites. It was discovered that human exposure to PAH metabolites induce and promote altered DNA by mechanisms described as increased intracellular pro-oxidant production as well as direct adduction to DNA. A unitary model for mammary carcinogenesis in humans was therefore hypothesised. If this hypothesis was proven to be correct it would account for the increase in breast cancer incidence in industrialised countries, and potentially suggest modifications to be made to inhibit PAH induced mammary carcinogenesis. (Morris and Seifter 1992)

Similarly, in more recent years there was an ecological study carried out in the US in 2015. This study was done to analyse the incidence of breast cancer in relation to ambient PAH emission concentration in varying counties within the US. This study agreed with Morris and Seifters hypothesis, and it was found that highly industrialised areas shared a higher incidence of breast cancer. (Stults and Wei 2018)

  • Data regarding PAH concentration was obtained by US EPA, and county-level data on the incidence of breast cancer was obtained. A linear regression was performed using SPSS 23 software for Windows to analyse the association between PAH emissions and breast cancer incidence. The data was refined in various ways. Data from unreliable county sources i.e Kalawao County of the Hawaii region were excluded. Furthermore Alameda, Contra Costa, Marin, San Francisco, and San Mateo counties in the San Francisco–Oakland region were also omitted due to the fact they had inaccurate PAH emission data. Womens breast cancer cases were also assessed and refined by age/family history/smokers and non-smokers etc. The more industrialized metropolitan regions, San Francisco–Oakland, Connecticut, Atlanta, Detroit, and Seattle, had a definite higher incidence of breast cancer, as compared to less industrialized regions, Hawaii, Iowa, New Mexico, and Utah. This proves that PAH exposure from ambient air could play a role in the increased breast cancer risk among women living in urban areas of the US. (Stults and Wei 2018)

Various other cross sectional studies were shown that PAHs may implicate breast cancer in animals such as rodents, however as stated the exact etiology of breast cancer for humans is still unknown. (Korsh et al. 2015)

  • A cross sectional study was done in 1996 in America where DNA-adducts of breast cancer patients undergoing a mastectomy were analysed, and noncancer patients undergoing reduction mammoplasty were to serve as a control. It was found in this study that environmental carcinogen exposure(namely benzo(a)pyrene), found in cigarette smoke, may be associated with the etiology of human breast cancer. The results showed that while aromatic DNA adducts of some kind were found in all cases, the concentration of them within cancer patients compared to controls was significantly higher. Furthermore it was found that benzo(a)pyrene DNA adducts were found in 41% of breast cancer patients, however in noncancer patients there was no evidence of benzo(a)pyrene DNA adducts. Therefore this implicates that benzo(a)pyrene could potentially cause breast cancer. (Rundle et al. 2000)
  1. The mechanism of exposure of PAHs

 

There are three mechanisms of exposure of PAHs that effect humans. These include; Inhalation, Absorption, and Ingestion. (Baird et al. 2005)

  • Inhalation is the most common mechanism of exposure of PAHs. They’re ubiquitous in air and therefore are easily inhaled, especially in urban areas where the concentration is higher. (Baird et al. 2005)
  • Ingestion is another common mechanism of exposure, PAHs are commonly found in processed/charred/grilled/smokes meats. PAHs are also readily deposited on arable land therefore contaminating crops which humans consume. PAHs are highly lipid soluble and therefore readily absorbed from the gastrointestinal tract of mammals. (Abdel-Shafy and Mansour 2016, VanRooij et al. 1993)
  • Absorption can also occur especially whereby people work within oil/tar industries and are constantly in contact with PAHs within coal/tar. (VanRooij et al. 1993)
  1. Cohort and Case Control studies on how PAHs cause Breast Cancer

 


Case Control Studies

A case control study is a study in which patients with a certain disease/outcome of interest (cases) are compared to patients do not have this disease/outcome of interest (control). These studies are crucial to examine and carry out when deciphering whether a certain chemical can implicate a disease, as it is easy to compare and contrast results. (The Himmelfarb Health Sciences Library, 2011) There has been many different case control studies done on how PAHs may influence breast cancer. However none of the studies have been conclusive, all need further study to be done.

  • A case-control interview study was carried out in Long Island 1996 to assess the relationship of breast cancer risk and residential proximity to industrial facilities including traffic. A number of post and pre-menopausal women in Nassau and Suffolk Counties in Long Island were observed. It was found that there was a significantly elevated risk of breast cancer among post-menopausal women who were subject to exposure from chemical facilities, however this elevated risk was not seen for premenopausal women. (Lewis-Michl et al. 1996)
  • Furthermore, a study done in 2005 was similarly carried out to measure of the exposure to PAHs in early life, and if it were to lead to the occurrence of breast cancer. Total suspended solids were used as a measure of PAHs. As in the above study, it was found in post-menopausal women whom were exposed to high concentrations ( >140 microg/m(3) ) of TSPs had a higher risk (2.42 more likely) of developing breast cancer than compared to lower concentrations (<84 microg/m(3)). However results for premenopausal women were shown that actually exposure to PAHs at early age may cause a reduction in the risk of breast cancer. (Bonner et al. 2005)
  • It has also been determined that many PAHs such as benzo[a]pyrene (BaP) are found within cigarette smokes. A case control study was done to assess smoking related DNA-adducts in breast tissue, and see if there is any correlation between their concentration and the incidence of breast cancer. To test this, benzo(a)pyrene diol-epoxide (BPDE)-induced mutagen sensitivity and polymorphisms of GSTM1 and GSTT1 were evaluated in a pilot case-control study of breast cancer. Blood samples were tested from 100 breast cancer patients and 100 controls. It was found that breast cancer patients had a higher frequency of chromatid breaks than controls, which was associated with a >3 times increase in the incidence of breast cancer. Therefore suggesting that sensitivity to BPDE-induced chromosomal aberrations may be a factor in developing breast cancer. (Silva et al. 2010) Furthermore there’s a sufficient amount of evidence that suggests there is a correlation between smoking and incidence of breast cancer. For example, smoking causes human bronchial cells to produce stress-induced unregulated cRNA transcripts. These transcripts can also be seen in breast cancer cell lines, therefore suggesting that smoking can up regulate ncRNAs in breast cancer. (Xiong et al. 2001)


Cohort Studies

A Cohort study is a study in which a group of samples/patients (cohorts)  which share a common factor (age/race etc), are followed and evaluated with respect to an outcome/disease to discover what exposure characteristics to each cohort may be associated with the outcome/disease. (Himmelfard Health Science library, 2011)

  • A cohort study was done with California teachers to measure the incidence of breast cancer in relation to hazardous air pollutants. This longitudinal study was carried out for 15 years, and from the initial 112,378 California Teachers Study participants, 5,676 women were diagnosed with invasive breast cancer. A modelled annual average ambient air concentration of MGCs from the US EPA were linked to cohorts addresses. And from this Cox proportional hazards model was used to find a 95% confidence interval of cohorts hazard ratio associated with their address. It was found that statistically significant associations between increased risk of breast cancer and residence in areas with high estimated ambient concentrations of notably propylene oxide, vinyl chloride along with PAHs. (Garcia et al. 2015)
  • A cohort study was done to determine under identical conditions the relative carcinogenic potency in the mammary glands of female rats of benzo[a]pyrene amongst other carcinogens. Each 30 day old female rats were given BaP weekly for 8 weeks, other rats were given carcinogens such as 1-nitropyrene (1-NP) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). 41 weeks after the last carcinogen administration for the rats, they were killed and assessed for mammary gland tumours. Both malignant and cancerous mammary gland tumours were found for rats treated with BaP, the highest level found for all carcinogens tested. Within this test rats were directly given concentrations of BaP regularly over a number of weeks, this therefore would cause for immediate direct effects to be seen. Although this is not comparable for human subjects, as they wouldn’t be given such high dosages at regular intervals. However, this study does provide evidence that BaP can implicate breast cancer in humans and that further study should be done to assess this. (el-Bayoumy et al. 1995)
  1. Likely mechanisms in which PAHs exert their effect.

 

Polycyclic Aromatic Hydrocarbons as stated are Endocrine Disrupting Chemicals (EDCs). An EDC is defined by the US EPA as ‘‘an exogenous agent that interferes with synthesis, secretion, transport, metabolism, binding action, or elimination of natural blood-borne hormones that are present in the body and are responsible for homeostasis, reproduction, and developmental process’. (Diamanti-Kandarakis et al. 2009)

These ultimately can disrupt and alter endocrine processes and cause severe consequences by altering normal mammary tissue development. This has been shown in both rodent and human models. The mechanisms of EDCs such as PAHs are broader than anticipated and extend further than just exerting actions through nuclear hormone receptors. (el-Bayoumy et al. 1995, Diamanti-Kandarakis et al. 2009, Xiong et al. 2001)

Generally speaking, upon exploration of PAHs causing cancer in humans, it has been seen in many studies that tumors develop where PAHs have been administered to the test subject. i.e gastric tumours after oral administration, skin tumours after dermal application. However studies also show that PAHs, benzo(a)prune in particular when administered the oral route (mechanism of exposure being inhalation/ingestion), that tumours are seen in the lungs, bladder and mammary glands. This causes many different epigenetic effects.(Knower et al. 2014)

Epigenetic effects PAHs can have on breast tissue can include:

  • Forming DNA adducts near methylation sites in breast epithelium and milk. Benzo[a]pyrene (BaP) metabolite BaP-diolepoxide (BPDE) has been found in breast milk. This therefore proves that these carcinogens penetrate ductal epithelial cells where most breast cancer is said to arise. (Knower et al. 2014, Gorlewska-Roberts et al. 2002)
  • Altering DNA methylation and histone modification patterns. (Knower et al. 2014)

Upon the exploration of exact AOPs of PAH’s causing Breast Cancer, little information was found. However, what was found is that PAHs are xenobiotics. Xenobiotics metabolism occurs in the liver. Therefore, after ingestion/inhalation/adsorption of PAHs into the body, they bind to the lipid membranes and are transported by lipoproteins in the blood. Here, two main pathways can occur. (Ewa and Danuta 2017)


Phase I

– three main pathways of activation can occur: (Ewa and Danuta 2017)

  1. formation of dihydrodiol epoxides catalysed by cytochrome P450 enzymes and epoxide hydrolase.
  2. formation of a PAH radical cation in a metabolic oxidation process by cytochrome P450 peroxidase activity.
  3. formation of ortho-quinones via oxidation of catechols by dihydrodiol dehydrogenase.


Phase II

– following the introduction of a polar group, conjugating enzymes usually add endogenous substituents, such as sugars, sulphates, or amino acids. This therefore increases water solubility, which in turn makes them easy to excrete. Although this process is generally a detoxication sequence, reactive intermediates may sometimes prove to be much more toxic than the original compounds. (Ewa and Danuta 2017)

However the most common mechanism seen by the exposure of BaP, the most common PAH is as follows:

  • In Phase I, oxidation reactions catalyzed by cytochrome P450 enzymes (CYPs) and hydroxylation occurs. The CYPs: CYP1A1 and CYP1B1 are highly inducible by the exposure to PAHs via the aryl hydrocarbon receptor (AhR). Once a complex is formed, AhR-PAH, a heat shock protein (Hsp90) is released. The complex is then translocated to the Hsp90’s nucleus. Here a heterodimer is formed with an AhR-Nuclear-Translocator (ARNT) which binds to DNA via the xenobiotic response element in the promoter region of the P450 genes. This therefore suggests a method by which PAHs assists in the role of tumorigenesis. (Ewa and Danuta 2017)
  1. How the PAHs effects are modified by interaction with other agents or interacts with genome to produce different problems for different genotypes.

PAHs carcinogenicity can be influenced by a variety of factors such as synergistic and antagonistic effects of other compounds which are emitted together with PAHs during incomplete combustion. (Barhoumi et al. 2014)

Most notably, a number of both in-vitro and in-vivo studies have shown that dietary supplementation with natural chemoprotective agents such as n-3 polyunsaturated fatty acids enhance anti-tumor action. Within an investigation in 2014, control fatty acids such as oleic acid (OA), linoleic acid (LA)) and docosahexaenoic acid (DHA) were used to test the effects on the uptake and metabolism of BaP in A549 cells. As stated above A549 cells activate BaP through the P450 system to form metabolites which can essentially prove to be carcinogenic. It was seen DHA treated cells showed significantly lower pyrene like metabolites, additionally DHA proved to have a lower abundance of carcinogen BaP 7,8-dihydrodiol and the 3-hydroxybenzo[a]pyrene metabolites compared to other treatments. Therefore proving that DHA supplements could potentially mediate BaP carcinogenic effects. (Barhoumi et al. 2014)


Conclusion

As stated various times within multiple reports and papers, the exact etiology of breast cancer in women is unknown.

However there is sufficient evidence to cause speculation as to if PAH implicates breast cancer in women. Various longitudinal studies have been carried out and there is evidence, as discussed above, to suggest that there’s a correlation between PAH concentration and the incidence of breast cancer. It has also been stated in various studies that the implication of PAHs causing breast cancer is higher in postmenopausal women than premenopausal. However so is the incidence of breast cancer.

There has been direct evidence to prove that PAH administration to rodents in studies can cause mammary gland tumours. However this does not directly relate to humans as the concentration of PAHs given to rodents would not directly correlate with what humans are exposed to.

In conclusion there is sufficient evidence to suggest PAHs cause breast cancer, and more direct studies need to be done.


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