Reflect on your personal current sense of power within your organization and the profession.

Reflect on your personal current sense of power within your organization and the profession.

• Reflect on your personal current sense of power within your organization and the profession;
• Do a self–assessment of your leadership skills by doing the How Good are your Leadership Skills? assessment at http://www.mindtools.com/pages/article/newLDR_50.htm
o How did you score? You do need not to reveal this in your paper, but hopefully it will guide you in how to apply the concepts to your own situation.
• Reflect on your motivation for increasing your power within your organization and/or within the nursing profession.
• Do a self–assessment of your leadership motivation by doing the assessment The Leadership Motivation Assessment found at http://www.mindtools.com/pages/article/newLDR_01.htm
o Again, it is not necessary to post your score but hopefully it will guide you in how to discuss your motivation at this point in time.
• Review the information on power in the Learning Resources and conduct additional research on your own to examine strategies that seem relevant and worthwhile for helping to enrich your power as a nurse leader.
• Identify specific strategies you can use to develop and leverage sources and types of power to achieve desired outcomes.
To Complete
Write a 2– to 3–page paper, not including the cover and Reference page, describing:
• A self–assessment of your current sense of power within your organization and the profession;
• A self–assessment of your motivation for increasing your power base;
• Write a detailed plan for enhancing your power as a nurse and a leader–manager, including specific strategies for achieving that plan. Be sure to include strategies for mobilizing the power of nursing for social change, empowering others, and building a personal power base.

Responses to Cancer: Behavioural- Emotional and Physical



Behavioural, Emotional, Physical and Cognitive Responses

Cancer is a deadly disease cause by uncontrolled division of abnormal cells and as a group, accounts for more than 14% of all deaths each year (Ahmedin, et al., 2008) and once, the individual finds out about his diagnosis with this deadly disease, the individual is likely to experience severe emotional, cognitive, physical and behavioural response since, everyone knows that untreated and even treated cancer in some cases tend to be life threatening. The severity of these responses varies individually and is dependent on several factors such as whether the event was surprisingly recognized or whether earlier complaints were present, plays a major role (Verwoerdt, 1973). Furthermore, it depends on personal experience with the disease, for example, if previous generations of the family had been diagnosed with cancer (Verwoerdt, 1973).

Behaviour is one of many responses which plays a huge role throughout the individual’s diagnosis and is most probable to change thoroughly. These Behavioural responses generally result from the genetic makeup, past experience and the Individual’s perception of the current situation (Snyder, 2011). The individual is likely to experience several behavioural change with certain steps and are likely to prompt restlessness, stress, searching for several answers, anxiety or even disbelief.

The first step during the behavioural response usually involve Pre-contemplative/unawareness stage (Miller & Rollnick, 2002). In this stage the individual is not interested in his diagnosis nor does he plan to do anything about it. The individual is completely in state of denial, unmotivated and resistant regarding his diagnosis. The individual is also likely to defend his current behaviour if others such as his doctor or family member’s try to intervene.

The second behavioural response stage involves contemplative phase where the individual starts to think about his life and his family which ultimately leads him to think about his diagnosis and treatment seriously (Miller & Rollnick, 2002). Most individuals tend to accept their problem at this phase and eventually start to plan about their future strategies to improve his and family’s life.

The third behavioural phase involves preparation where the individual tend to realise that a change is inevitable (Miller & Rollnick, 2002). The individuals also incline to realise the severity and seriousness of his cancer and usually makes several decisions and commitments to change the outcome of his diagnosis. This stage usually tend to be a period of transition and therefore, tend to be quite short.

In the fourth behavioural phase, the individual tries to implement several strategies to start a “new” life (Miller & Rollnick, 2002). The individuals going through this phase also tend to be realistic and open minded in terms of receiving help and support. This step normally is the “willpower” stage for most individuals going through hardship and often tend to reward themselves to enhance motivation and self-confidence which often help them to deal with personal and external pressures.

The fifth and last behavioural phase include maintenance where many individuals try to consolidate changes in their behaviour, to maintain the ‘new’ status quo and to prevent relapse or temptation (Miller & Rollnick, 2002). The individual normally tend to see any previous behavioural change undesirable, unnecessary and customarily tries to implement new working strategies by the means of seeking help, usually a doctor.

Whilst the individual’s behaviour is fluctuating, emotion is likely to build up the moment the individual finds out about his cancer. These emotions often trigger responses such as feelings of fear, anger, rage, sadness and dejection.Such mood swings are tend to be normal andmost individual incline to live through this cold baths of feelings for a long time until the individual finds his way for himself to accept the disease.

In most individuals, the diagnosis of Cancer triggers shock as the first emotional response (Tsao, 2010) which usually last from hours to days. Many individuals feel alienated, frozen and cannot think clearly. In this stage the patient is unable to conduct basic necessities of his life, requires help and constantly shows his emotions.

The second response of emotion involves denial where the individual attempts to shut out the authenticity and magnitude of his situation by developing a fabricated, desirable reality (Tsao, 2010).

Once the individual accepts his fate with the diagnosis and overcomes the denial, the third phase of emotion includes wrath and anger. During this phase the individual constantly thinks about his diagnosis to be unfair and ask questions such “Why is it always me? It’s not fair!”; “How can this transpire to me?” (Tsao, 2010).

The next phase usually involve bargaining (Tsao, 2010) where many individuals try to negotiate with their fate by constantly making statements such as “I’ll do anything to live for few more years” therefore creating a sense of hope. In this stage, the individuals also tend to isolate themselves from others and even prevent any human interactions.

After the individual realises that his fate cannot be bargained depression starts to take place as a fifth emotional phase (Tsao, 2010). In this phase, the patient is dealing with his diagnosis and the intensive life of contradictory feelings which might lead the individual to the utmost limit of his mental capacity. The individual’s psychological immune system is also likely to be flooded with stimuli, which might often results in fatigue, hopelessness and resignation.

Once, the depression is overwhelmed acceptance, is likely to take place as a last step of emotional response (Tsao, 2010). In this phase the individual usually accepts his fate and makes statement such as “I have cancer and I will live with it” as a motivation. Once the individual stabilises himself on this setting, he stands on a firm foundation for a self-determined life and inclines to makes new plans and to actively solve his problems.

Cognitive is another major part the individual’s response once the diagnosis has been revealed. In this phase, several negative thoughts tend to arise whilst the individual is interacting such as communicating, reading, watching television, listening to radio etc. (Park, 2013). cognitive changes in patients suffering from cancer may possibly be caused by disease, cancer treatment, complications of the treatment, comorbid conditions, side effects of drugs, other physiological responses to diagnosis of cancer (Park, 2013). In this response, the individual rarely thinks positively and normally tends to thinks rationally and therefore several suicidal and self-harm thoughts tend to arise. This response takes place whilst emotional and behavioural response is developing and usually ends once the individual’s treatment has been completed.

Several physical response such as hair/weight loss, inability to speak about the cancer without experiencing grief, overreacting to minor events, loss of appetite, fatigue etc. are likely to arise throughout the whole process of cancer and its treatment. These physical changes are likely to make the individual feel shameful, guilty, paranoia and even Intellectualization. These types of physical changes are usually seen once the emotional, behavioural and cognitive responses takes place (Moos & Schaefer, 1984).

In conclusion, the onset of any illness gives rise to a wide range of different responses such as emotional, cognitive, physical and behavioural which varies greatly from individual to individual, even in those with the same condition. However, from above information regarding various responses, it is clear that the above responses stated are likely to arise at various point of any illness.

References

Ahmedin, J. D., Siegel, R., Ward, E. D., Hao, Y. D., Xu, J. D., Murray, T., & Thun, M. D. (2008). A Cancer Journal for Clinicals.

Cancer Statistics

, 72. doi:10.3322/CA.2007.0010

Miller, W. R., & Rollnick, S. (2002). Motivational Interviewing: Preparing People for Change.

Behavioural change

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Moos, R., & Schaefer, J. (1984).

Coping with Physical Illness.

Springer US. doi:10.1007/978-1-4684-4772-9_1

Park, H.-J. (2013). Structural and Functional Brain Networks: From Connections to Cognition.

Cognition responses, 342

(6158), 1238411 -1238411. doi:10.1126/science.1238411

Snyder, J. (2011). Adult hippocampal neurogenesis buffers stress responses and depressive behaviour.

Behaviour, 476

(7361), 458-461.

Tsao, C. (2010). Kubler-Ross.

Stages of Grief, 34

(1), 38.

Verwoerdt, A. (1973).

Psychopharmacology and Aging.

Springer US. doi:10.1007/978-1-4684-7770-2_16

Applying Kants Ethical Theory to Nursing

Immanuel Kant was born in 1724 in Königsberg, which is today the city of Kaliningrad in the Russian exclave of Kaliningrad Oblast (Watkins, 2002). He was raised in a Pietist household that stressed intense religious devotion, personal humility, and a literal interpretation of the Bible (European Graduate School [EGS], 2010). Kant wrote numerous works in his lifetime but most of Kant’s work on ethics is presented in two works, The Foundations of the Metaphysics of Morals written in 1785, and the Critique of Practical Reason written in 1787 (McCormick, 2006).

In order to understand Kant’s ethical views, his views on duty, reason, freedom, and good will should be explored. Freedom plays an important role in Kant’s ethics. A moral judgment presupposes freedom (McCormick, 2006). Also, freedom is a notion of reason, so without the assumption of freedom, reason cannot proceed. On the other hand, reason can only be satisfied with assumptions that practical observation cannot support. Reason seeks knowledge or understanding that it cannot comprehend (Williams, 2009).

The question of moral action is an issue for rational beings. There is nothing in a rational beings character to waver. It will always match the dictate of reason. Humans are not wholly rational beings. We can either follow our natural instinct or non-rational impulse. Thus, rules of conduct are needed to guide human’s actions.

Will is the ability to act according to the law. Outcomes of our actions are beyond our control. The only thing we can control is the will behind the action. Morality of an act must be assessed in terms of the impulse behind it. Kant says “good will” as the only thing unconditionally good because it cannot be used for ill purpose.

Kant argued that moral requirements are based on a standard of rationality he dubbed the Categorical imperative. Categorical imperative is defined as the standard of rationality from which all moral requirements are derived (Categorical imperative, 2007). It is an imperative because it is a command. It commands us to exercise our wills in a particular way. It is categorical because it is unconditionally and applies to everyone at all times (Hinman, 2006). CI requires an autonomous will. It is the presence of this self-governing reason in each person that Kant offered decisive grounds for viewing each person as possessed of equal worth and deserving of equal respect.

There are three maxims or categorical imperatives that Kant’s theory are based on. The first categorical imperative is Universalisability which states that, “Act only according to that maxim whereby you can at the same time will that it should become a universal law.” The second categorical imperative is the Law of Nature which states that, “Act in such a way that you treat humanity, whether in your own person or in the person of any other, always at the same time as an end and never merely as a means to an end.” The third categorical imperative is known as the Kingdom of Ends states that, “every rational being must so act as if he were through his maxim always a legislating member in the universal kingdom of ends” (Kant, n.d., ¶ 43).

The first maxim shows Kant’s ethical theory asserts that right actions are those that practical reason would will as universal law. In other words, if the course of action someone plans to take can be willed upon everyone then it is an ethical choice (Davison, 2006). A moral maxim must have universality and could be applied to any rational being.

The second maxim is often seen as introducing the idea of respect for persons, for whatever it is that is essential to humankind (Johnson, 2004). The second maxim expounds on the perfect duty concept in preventing exploitation of others or anyone as a means to an end.

The third maxim combines the others in that it requires that we conform our actions to the maxims of a legislator of laws and that this lawgiver lays down universal laws, binding all rational wills including our own. The idea behind this formulation is that our fundamental moral obligation is to act only on principles which could earn acceptance by a community of fully rational agents.

Kant used the term good will to define the resolve to act purely in accordance to one’s duty. He believed that using reason, a person could work out what one’s duty was. Good will is making moral decisions without considering personal happiness or pain avoidance. Duty must be done whether a person wants to or not(Johnson, n.d.). Duty consists of bare respect for lawfulness. x

Explanation of Watson’s Theory of Caring

Watson’s first major publication, Nursing: The Philosophy and Science of Caring, began as a class notes for a course she was developing (Tomey & Alligood, 2002). This publication was developed in 1979, and revised in 1985 and 1988. According to Watson, the book emerged from her “attempt to bring meaning and focus to nursing as an emerging discipline and distinct health profession with its own unique values, knowledge and practices, with its own ethic and mission to society (Watson, 2007, ¶ 1). Watson used the term “carative factors” to describe the framework for the core of nursing values. These carative factors complemented conventional medical “curative factors” by adding the theory of human caring to the medical focus of cure (Watson). Watson’s major assumptions of the science of caring in nursing are the following:

Caring can be effectively demonstrated and practiced only interpersonally.

Caring consists of carative factors that result in the satisfaction of certain human needs.

Effective caring promotes health and individual or family growth.

Caring responses accept person not only as he or she is now but as what he or she may become.

A caring environment is one that offers the development of potential while allowing the person to choose the best action for himself or herself at a given point in time.

Caring is more “healthogenic” than is curing. A science of caring is complementary to the science of curing.

The practice of caring is central to nursing (Watson, 1979, p. 8)

Watson based her theory for nursing practice on 10 carative factors (Watson, 1979, p. 9). The first three factors served as the “philosophical foundation for the science of caring” (Watson, 1979, p. 10).

The formation of a humanistic- altruistic system of values.

Humanistic and altruistic values are learned early in life but can be greatly influenced by others and life experiences. This factor is defined as satisfaction through giving and extension of the sense of self (Watson, 1979).

The instillation of faith-hope.

This factor facilitates the promotion of holistic nursing care by developing effective nurse-patient relationship.

The cultivation of sensitivity to one’s self and to others.

The recognition of feelings leads to self actualizations through self acceptance for both the nurse and the patient. When the nurse is able to acknowledge their feelings, they are more sensitive to the feelings and needs of their patients.

The development of a helping-trust relationship

The development of a helping-trust relationship between the patient and the nurse is crucial for the expression of both positive and negative feelings. This helping-trusting relationship develops rapport and caring. It involves congruence, empathy, nonpossessive warmth, and effective communication (Watson, 1979).

The promotion and acceptance of the expression of positive and negative feelings.

The expression of feelings is a risk taking experience for both the nurse and the patient. The nurse and the patient must be prepared for each moment of expression.

The systematic use of the scientific problem-solving method for decision making

Use of the nursing process brings a scientific approach to decision making.

The promotion of interpersonal teaching-learning.

This factor allows the patient to be well informed about their care in order to participate in their plan of care and healthcare decisions. The nurse is the facilitator with the use of teaching-learning techniques appropriate for the patient.

The provision for a supportive, protective and /or corrective mental, physical, socio-cultural and spiritual environment.

The nurse must be aware of the external and internal factors that may affect the well being of the patient. The nurse also must provide comfort, privacy and safety as a part of this carative factor (Watson, 1979).

Assistance with the gratification of human needs.

The nurse must recognize the biophysical, psychological, and intrapersonal needs of the patient. The patient must satisfy lower order needs before attempting to attain higher order needs. Watson suggested that the nurse also must provide comfort, privacy and safety as a part of this carative factor (Current Nursing, 2009).

The allowance for existential-phenomenological forces.

This factor helps the nurse view the patient holistically while attending to the patient’s needs. Watson considers this factor to be difficult to understand but is included to provide thought provoking experience leading to a better understanding of the self and others (Watson, 1979).

Nursing: Human Science and Human Care- A Theory of Nursing was published in 1985. The purpose of the book was to address some of the problems that still existed in nursing (Tomey & Alligood, 2002). Her most recent book, Caring Science as Sacred Science (2005), “seeks to bridge paradigms as well as point toward transformative models for the 21st century” (Watson Caring Science Institute, 2009).

As Watson continued to evolve her theory, she introduced the concept of clinical caritas process (Watson, 2005). The caritas process has greater spiritual dimension and overt show of love compared to the original carative factors (University of Colorado Denver, 2007).

Embrace altruistic values and practice loving kindness with self and others.

Instill faith and hope and honor others.

Be sensitive to self and others by nurturing individual beliefs and practices.

Develop helping – trusting- caring relationships.

Promote and accept positive and negative feelings as you authentically listen to another’s story.

Use creative scientific problem-solving methods for caring decision making.

Share teaching and learning that addresses the individual needs and comprehension styles.

Create a healing environment for the physical and spiritual self which respects human dignity.

Assist with basic physical, emotional, and spiritual human needs.

Open to mystery and allow miracles to enter (Watson Caring Science Institute, 2007).

Watson (1999) characterized a transpersonal caring relationship as a special kind of human care relationship that depended on the nurse’s moral commitment in protecting human dignity, nurse’s caring consciousness to preserve the embodied spirit, and to potentially heal because of this connection (Watson, 2007). Transpersonal relationship is a deeper connection of the mind, body and spirit, and the intentional caring for the whole being of the patient. The relationship is unique because the nurse and the patient bring their individuality to the moment, and if a different nurse or patient is injected to the moment, a different experience would exist.

According to Watson (1999), a caring occasion is the moment when the nurse and the patient come together with their uniqueness and an occasion for caring is created. During the moment that the nurse and the patient are together, each would decide how to react and to take advantage of the moment to heal and to share. The whole caring-healing-loving consciousness is contained within a single caring moment (Watson, 2007).

Explanation of Benner’s Novice to Expert theory

Benner has numerous influences in her body of work. She acknowledges that Virginia Henderson influenced her in her nursing thinking (Tomey & Alligood, 2002). She also worked as a research assistant for Richard Lazarus in University of California, Berkeley. He mentored her in the field of stress and coping. Hubert Dreyfus was a philosophy professor at Berkeley during the time Benner was getting her doctorate degree. He introduced her to phenomenology. Hubert Dreyfus, together with Stuart Dreyfus, developed the Dreyfus Model of Skill Acquisition which Benner applied in her work From Novice to Expert (Benner, 1984).

Benner’s work as the author and the project director of a federally funded grant, Achievement Methods of Intraprofessional Consensus, Assessment, and Evaluation (AMICAE) led to the publication of From Novice to Expert (Tomey & Alligood, 2002). Benner and Wrubel further explained the background to this study in The Primacy of Caring: Stress and Coping in Health and Illness (Benner & Wrubel, 1989).

In the AMICAE project, 1200 nurse participants completed questionnaires and interviews, with 51 participants observed by trained researchers. Paired interviews were conducted with preceptors and preceptees, and nurse clinicians with newly graduated nurses and senior nursing students. These interviews “aimed at discovering if there were distinguishable, characteristic differences in the novice’s and expert’s description of the same clinical incident” (Benner, 1984, p. 14). The interviews also “described characteristics of nurse performance at different stages of skill acquisition” (Benner, p. 15). This study led to the use of Dreyfus’ five levels of competency, namely novice, advanced beginner, competent, proficient, and expert, to describe skill acquisition in the nursing practice. Each stage builds on the previous one as the nurse gains clinical experience.

By analyzing the transcript from the interviews, 31 competencies emerged from the nurse’s detailed description of patient care. Each of these domains was described with the related competencies from the exemplars describing nursing practice (Tomey & Alligood, 2002). From these competencies, 7 domains were derived according to similarity of function and intent:

The helping role

The teaching-coaching function

The diagnostic and patient-monitoring function

Effective management of rapidly changing situations

Administering and monitoring therapeutic interventions and regimens

Monitoring and ensuring the quality of healthcare practices

Organizational work-role competencies (Benner, 1984)

By using the model in nursing practice, Benner noted that “experience-based skill acquisition is safer and quicker when it rests upon a sound educational base” (Benner, p. xix).

Benner defined skill and skill acquisition as the actual use of skilled nursing intervention and clinical judgment skills in actual clinical situations (Benner, 1984). This accumulation of nursing skill and knowledge is relevant only when these skills and knowledge are used to improve patient outcomes and improve patient care.

Benner added to her research from the first study to a six year study of 130 hospital nurses, the majority from the critical care areas. She presented the results of the study on her book Expertise in Nursing Practice: Caring, Clinical Judgment, and Ethics (Benner, Tanner, & Chesla, 1996). Benner states, “In the study we found that examining the nature of the nurse’s agency, by which we mean the sense and possibilities for acting in particular clinical situations, gave new insights about how perception and action are both shaped by a practice community.”(Benner et al., p. xii). Phase two of this study also produced nine domains of critical care nursing practice. They are:

Diagnosing and managing life-sustaining physiological functions in unstable patients

The skilled know-how of managing a crisis

Providing comfort measures for the critically ill

Caring for the patient’s families

Preventing hazards in a technological environment

Facing death: end of life care and decision making

Communicating and negotiating multiple perspectives

Monitoring quality and managing breakdown

The skilled know-how of clinical leadership and the coaching and mentoring of others (Benner, Hooper-Kyriakidis, & Stannard, 1999).

With a sound educational base, nurses develop skills and patient understanding through clinical experiences. Benner proposed that the “know-how” or gaining of knowledge and skill can be acquired without the “know-to” or learning the theory (Benner, 1984). Significant clinical experience is a prerequisite to attaining the higher stages of skill acquisition (Dracup & Bryan-Brown, 2004). x

Application of Benner’s work in nursing practice

Benner’s work, especially the five stages of skill acquisition, has been applied in administration, education, practice, and research (McEwen & Wills, 2007). Benner’s seven domains of nursing roles have been used by Schools of nursing in their school philosophy (Liberty University Department of Nursing, 2009), and also in many hospital institutions (Nuccio et al., 1996, Alberti, 1991). Benner’s novice to expert skill acquisition was used in establishing expectations for both staff and administration in the implementation of laptops in the home care setting (Larrabee, 1999). In another application of Benner’s levels of skill acquisition, the University of Maryland, Baltimore School of Nursing used Benner’s concept to establish protocols for the development of patient care simulation for students (Larew, Lessans, Spunt, Foster, & Covington, 2006). Benner’s model was also used to guide nurses in taking care of handicapped children in the school setting (Pesata, 1994). Benner’s skill acquisition framework has also been used in research (Cusson & Strange, 2008; Lyneham, Parkinson, & Denholm, 2008; Fuller & Conner, 1997; Maynard, 1996).

Clinical Nursing Situation

All names used in this narrative have been changed to protect anonymity. Aaron was 28 years old when he was admitted in the community hospital due to meningitis. He stayed in the hospital due to complications like sepsis and bacteremia. He lost a tremendous amount of weight, and eventually his muscles atrophied, and his joints became contracted. His parents were unable to cope with the situation so they stopped visiting him in the hospital.

Aaron was transferred to the County hospital where I worked. I first met Aaron when he was admitted to the intensive care unit. He came in with sepsis and pneumonia which required him to be connected to the mechanical ventilator for support. His 80 pound thin frame was evident especially since he was six foot tall. The only command he could follow was to look at you.

For the whole week, I was assigned to him. I learned to change the channels to any sports related shows. I would tell him about sports games I watched or read about. He would just look at me waiting to hear more. I learned to suction him without triggering him to have bronchospasm. By the end of the week, I saw the hospital’s palliative care physician come in to check on the patient. The physicians, after much discussion with Aaron’s parents, decided to disconnect Aaron on the weekend from the mechanical ventilator and to start comfort measures as soon as he was removed from the ventilator.

The next day, I was the nurse in charge of the whole unit. I was not initially assigned to Aaron but had to take over his care when the nurse originally assigned to him could not handle the emotional situation. As I walked in the room, I saw Aaron struggling. He was breathing loudly in the 40s. It sounded like a saw going through a hollow tree. He was using his accessory muscles to breathe. His heart rate was double where his baseline heart rate was. He was diaphoretic. This was not a comfortable death.

I increased the morphine rate to 10 milligrams per hour as ordered. I wet a washcloth with cold water and started wiping Aaron’s forehead. He looked at me but instead of the sad look, he had a painful look and tears in his eyes. I turned on the television to the music channel where it was playing soft music. All these measures did not help Aaron’s respiratory distress. Aaron’s attending physician walked in. He suggested giving a bolus of and starting propofol drip to ease Aaron’s respiratory distress. I gave the bolus and started the propofol drip.

Aaron was breathing in the 10s and his heart rate was back to where his baseline was. Dr Herms sat down beside Aaron and held his hand. I continued to wipe his forehead, and to talk to Aaron. A few minutes after starting the propofol drip, Aaron’s breathing stopped and he passed away.

Application of Kant’s Ethical Theory

In order to adhere to the categorical imperatives and as a result make ethical choices, one must distance oneself from their emotions. It is a matter of stepping out of ourselves and thinking of the effects our decisions have on others.

In applying the first CI by Kant, “Act only according to that maxim whereby you can at the same time will that it should become a universal law”(Immanuel Kant, 2009, ¶ 44), we must first formulate a maxim for the reason of the action. Second part is to use that action as a universal law governing all rational agents. The third part is whether to consider the maxim as conceivable in a world governed by laws. The last part is whether you as an agent will act on the maxim. If you could do all steps, the action is morally permissible. In this case, a high dose of sedative and narcotic is given to help with Aaron’s respiratory distress. This action is permissible for end of life measures and is conceivable in today’s world. Thus, the administration of high dose of narcotics and sedatives for respiratory distress is morally permissible.

The second CI states that “Act in such a way that you treat humanity, whether in your own person or in the person of any other, always at the same time as an end and never merely as a means to an end” (Immanuel Kant, 2009, ¶ 44). Aaron being a rational being demands respect. As a human being, Aaron has the right to die peacefully and with less suffering. Any symptoms of his struggle and suffering should be addressed in order to achieve his due end.

As the nurse who volunteered to take over a coworker’s assignment, I had the free will to choose to help or not. Since I know Aaron, I understand the situation and agree with the plan of care. I was bound by my duty to help Aaron die with little or no pain. The health care providers assigned to Aaron’s case had the right motive to allow him to have a peaceful humane death. x

Application of Watson’s Theory of Caring

Embrace altruistic values and practice loving kindness with self and others.

This system of values is what makes the nursing profession human. Each nurse brings to the profession their own set of altruistic and humanistic values that each have learned in their lifetime. In this case, my value for a life is strong. My desire for each person to die with dignity and with someone by their side is important. So even if I was busy that day being in charge, I dropped everything in order to assist the physician to give the necessary medications, and just simply to be there for Aaron until he passed away.

Instill faith and hope and honor others.

This factor facilitates the promotion of holistic nursing care and describes the nurse’s role in the development of effective nurse-patient interrelationship. Since I took care of the patient for a week, I learned small nuances about the patient to know what his needs are. I had learned what sports teams he liked, and what kind of songs he listened to. These may seem small things, but when you look at a person, you see everything about them. As nurses, we aim to foster that faith of our patients in us that we are going to do what is best for them.

Be sensitive to self and others by nurturing individual beliefs and practices.

The recognition of feelings leads to self actualization through self acceptance. It is hard to know if Aaron has accepted his fate (since he was nonverbal), but personally, I was able to accept that everything was done for this patient. We had done everything that we could, and at that point we had to assist him to his peaceful death.

Develop helping-trusting-caring relationships.

The development of a helping-trusting-caring relationship involves empathy, warmth, and effective communication. With the time that I worked with Aaron, I told him the treatment, and activities we planned to do. I recognized that even if he wasn’t able to vocalize his needs, he still had feelings and needs.

Promote and accept positive and negative feelings as you authentically listen to another’s story.

The positive and negative expression of feelings was more on the parents’ side. I never saw his parents come to visit in the morning but I have heard that the physicians and social workers were in regular contact with the family. During the course of the end of life measures, there were discussions between the medical and nursing staff on how to make things easier for Aaron. Although Aaron was not able to verbally express his feelings, his nonverbal cues like facial grimacing, tearing up, and labored breathing was enough to communicate his needs.

Use creative scientific problem-solving methods for caring decision making.

After we extubated Aaron, he went into respiratory distress, in spite of the morphine drip and other medications given. After recognizing that the treatment was not effective, the palliative care doctor consulted another attending physician. A decision was made to give propofol. During the time of discussion, other nursing measures were instituted like music, touch, and cold compress to the head. The scientific problem solving method used involved assessment, plan, treatment, and evaluation of treatment given.

Share teaching and learning that addresses the individual needs and comprehension styles.

Although no active teaching-learning experience was done, Aaron was still informed of the treatment, medication, and plan of care. The teaching-learning process was more dynamic between the nursing and medical staff about end of life measures. All the teaching-learning process was still directed towards the care of Aaron.

Create a healing environment for the physical and spiritual self which respects human dignity.

I was focused on the adequate pain relief, supportive caring environment for Aaron. He was never left alone. All the healthcare providers were communicating with Aaron what was being done.

Assist with basic physical, emotional, and spiritual human needs.

Biophysical, psychophysical, psychosocial and intrapersonal needs of the patient were attempted to be met. According to the Aaron’s family, he was neither religious nor spiritual so that was respected.

Open to mystery and allow miracles to enter

As Aaron’s health care providers, we allowed ourselves to be instruments for his care. The miracle is the passing away of suffering and start of after life for Aaron.

The transpersonal relationship between Aaron and I occurred from the moment I was assigned to him, and attempted to get to know his history and needs. We each brought our uniqueness to the relationship. My acceptance of Aaron’s situation and my commitment to take care of him helped foster a healing environment for Aaron. The caring moment occurred whenever I would seek to find out what his needs are, and attempting to fulfill his physical, social, psychological, and spiritual needs.

Application of Benner’s Novice to Expert Theory

In applying Benner’s work in the clinical exemplar, the prerequisite in providing appropriate nursing care is through knowing the patient. In this case, getting to know Aaron was harder since he was nonverbal and his family was not there to answer questions regarding Aaron. Benner called these patients the silent patient (Benner, 2002). I worked in the critical care unit for five years. This time gave me the opportunity to acquire skills in being attentive to patient’s needs especially those who are sedated or paralyzed, and acquire knowledge and expectations in the progression of disease and end of life measures.

In applying Benner’s seven domains of competencies, I was able to use majority of the functions. I was in the helping role in managing Aaron’s pain and discomfort. The teaching-coaching function allowed me to coach Aaron in slowing down his breathing. I was able to monitor Aaron’s progression, and this allowed me to effectively manage his changing situation. I was able to administer therapeutic interventions to ease Aaron’s pain. Through it all, I was working with the health care team.

In Benner’s nine domains of critical care nursing practice, I will focus on my function as providing end of life care for Aaron. Benner described dying as “central to human identity, and it forms a part of everyone’s history (Benner, Kerchner, Corless, & Davies, 2003, p. 558). She further states that “palliative care should address symptom management comprehensively and flexibly so that the person’s comfort and dignity are preserved” (Benner et al., p. 558).

As part of the healthcare team who provided care to Aaron’s last hour, I made sure Aaron had a comfortable dignified death by providing the best care I have learned through all my years of clinical experience. x

Conclusion

Literature Review of Post Operative Pain Management

1. INTRODUCTION

The aim of the project will be to provide a critical review for the improvement of clinical and medicinal management of post operative pain. If the points put forward are taken into consideration then the dissertation will not only prove beneficial if the reader is a clinician as it can also can be read and understood by a patient or a student for literary purposes or wants to find ways to improve their treatment before they undergo surgery.

Project Question – The primary research question of the dissertation is: “How, if possible, can post operative care measures be improved to help the patient overcome pain, whilst maintaining standards of NICE (National Institute for Health and Clinical Excellence) guidelines.

2. LITERATURE REVIEW

This section would be dedicated to the background of the dissertation. The reader should gain an understanding behind the physiology of acute pain. The delivery of drugs is also an important factor as different procedures for their delivery depend on the patient’s condition and requirements. Quality measures must also be taken into consideration as each patient should be attended to as a unique case no matter how similar the requirement.

The following must also be taken into consideration when presenting background information:

NICE Guidelines for assessment of changes in post operative pain management strategies over the last 3 years (to base the project on current information)

Evidence (tabular, graphical or statistical) to support different efficacies between drug modalities.

Most commonly used drugs, further pinpointing the use of specific drugs for patient’s suffering from different conditions.

2.1. Importance of post operative pain management

This section should elaborate on why this kind of care is necessary. One good scenario based example can involve a busy surgical ward:

Using journal literature, one good example can be given where short supplies of patient controlled analgesic pumps (PCA pumps) are present. In such a scenario, post-operative ward patients may be required to be earlier withdrawn from the equipment to make this treatment available for the next patients leaving the theatres. Therefore, once these pumps are removed, analgesic drug therapy is required to treat pain.

Successful implementation of pain management can result in patience comfort and satisfaction; therefore reputation of the hospital is well preserved.

2.1.1 Effect on Patients and families

Ethical/Cultural issues which surround post operative pain management, especially in patient groups including:

– Children

– Elderly

– Pregnant Women

– Cancer/Terminal Patients

– Patients administered with high drug dosage during operation

– Those with high risk due to drug allergies

2.1.2 Effect on Health Costs

Little data is available addressing the costs of post operative pain management. Such knowledge can help the reader’s understanding of caregiver choices related to direct medical costs, i.e. route of medication, type and required frequency. Therefore this can be a good idea to help improve pain strategy.

2.2 WHY SHOULD POST OPERATIVE MANAGEMENT OF PAIN BE IMPROVED?

2.2.1. How current post-operative pain management strategies work

Sedation Scores: The scores test whether a patient is easily aroused and to help prevent them from overdosing. There are 3 important factors which make up the sedation scoring system:

(i) It should cause minimal disturbance to the patient

(ii) be simple to use

(iii) be incorporated as a part of the patient’s routine assessment

Sedation scores create an impact on patient safety as respiratory depression may occur as a result from use strong drugs, such as narcotics. Identification or tracing these forms of drugs may be difficult and therefore lead to respiratory depression unnoticed.

Therapeutic Modalities: Opioids, Non-Steroidal Anti-Inflammatory (NSAID), COX-2 Inhibitors

Regional Techniques: Epidural, spinal analgesia contribute towards successful surgical outcome through progressive decrease in intra-operative blood loss, incidence of thromboembolic events, post operative catabolism, improvement of vascular graft blood flow and post operative pulmonary function.

Non-pharmacological techniques: Electrical-stimulation of peripheral nerves

2.2.2 Ineffective Drugs and Procedures

Choice of drug may have little or effect on pain

Method of Drug delivery may not allow the drug to work at its optimum efficacy

3. UNRESOLVED ISSUES

3.1 Multimodal Analgesia

The concept comes with the aim to combine analgesics with additive or synergistic effects.

However, combinational use of drug classes can pose as a risk to patients due to differing mechanism of drug action, side-effect profile of individual drugs and efficacies.

3.2 Pre-operative Analgesia leading to post-operative outcomes

Clinicians assume post-operative pain relief can lead to better clinical outcomes to benefit the patient and hospital finances. A few named examples of improved clinical outcomes include the following:

– Reduced organ dysfunction

– Decreased Morbidity

– Shorter hospital stay

Problems are associated with these assumptions as attention should be shifted to effects which are clinically meaningful for example:

– Resumption of dietary intake

– Recovery of bowel and bladder function

– Resumption of normal lifestyle and physical activity

– Long term recovery (i.e. less chronic pain)

4. NEW FINDINGS

.This section should elaborate on any novel discoveries made in the following:

4.1 PROCEDURES

4.1.1 DRUG DELIVERY

– Intravenous Patient-Controlled Analgesia (IV PCA)

– Patient-Controlled Epidural Analgesia (PCEA)

– Patient-Controlled Regional Analgesia (PCRA)

– Patient-Controlled Intranasal Analgesia (PCINA)

– Fentanyl Iontophoretic Transdermal System (ITS)

Post-operative pain has shown significant improvement through the introduction of patient-controlled analgesia (PCA) delivery. Current PCA procedures (including intravenous or epidural routes) show limitations where requirement for indwelling catheter remains and time is also needed for system set up and use.

New PCA technology have addressed drawbacks to existing equipment, however using complex new and improved technology can be an issue as training is required. An example of new technology includes “smart” intravenous PCA infusion pumps – to help make the delivery of analgesic drugs safer. Another example includes needle free options such as intranasal delivery and fentanyl HCl iontophoretic transdermal system for transdermal delivery

4.2 DRUGS

Analogues or isoforms of current effective drugs, which show more potential in phase II or III clinical trials. Diagrams of these isoforms can be provided with a brief description on its mechanism of action and use.

Pre-emptive analgesia: The drug is administered before the painful stimulus occurs to substantially reduce or prevent pain and any further analgesic requirement. This hypothesis of protecting the nervous system pre-emptively has provoked numerous clinical studies to take place; therefore it is an attractive area worth looking into. For example, administration of epidural fentanyl or bupivacaine prior to surgical incision in male patients that went through radical prostatectomy.

Dexmedetomidin: A centrally active alpha- 2-adrenergic agonist that is highly selective to provide both sedation and analgesia without significant ventilatory depression.

Regional anaesthesia and local anaesthetics: Adjuvants, Gabapentin, Ketamine

5. IMPACT OF IMPROVING POST OPERATIVE PAIN MANAGEMENT

Consistent efficacy across a number of hospital/surgeries

Right kind of treatment received at the right time means less complication or risk of clinical malpractice

Improvement of pain management strengthens our knowledgebase of drugs in the market

Space can be given to perform clinical trials where drugs may potentially be administered without the use of equipment, therefore reducing costs

6. DISCUSSION / CONCLUSION

The discussion of the project should draw upon the various criticisms made towards drugs and procedures in order to provide a rational argument for a route for improvement.

For example in terms of procedures, there remains an important need for clinicians to implement evidence-based, procedure specific protocols for new drugs, especially those which are shown to have high efficacy in clinical trials. Additionally, drug profiles should be modified to meet the need of individual patients and therefore enhancing the quality of post operative pain management.

A combined education/training approach amongst healthcare providers (i.e. anaesthesiologists, surgeons, nurses and physiotherapists) has been shown to improve quality of a patient’s recover process, reducing hospital stay or morbidity. The importance of assessing pain in different patient groups is a vital point. For example, an adult would react differently to pain than a child would. Furthermore being able to segregate patient groups can further aid provision of the right kind of drug rather than using generic treatment to expect optimal recovery.

Once these arguments are compared and discussed, it would be worth having the final conclusion to mention the impact of improvement (linking section 5) taking into consideration the budget cuts within the NHS as a result of the economical downturn (recession) and how making services more efficient would bring more benefits than drawbacks to the NHS as a whole.

Social Self

For this assignment, you will choose one or two social media platform(s) (Instagram, Facebook, Twitter, YouTube, Snapchat, etc.). Once you have chosen, in 500-750 words, do the following:

  1. Describe the self-enhancement and self-verification motives for self-esteem.
  2. Evaluate the posts/pages you see through the lens of self-presentation.
  3. Discuss which motive (self-enhancement or self-verification) is most evident in the sites you viewed. Provide examples, but do not include identifying information (names, handles, gender, etc.).
  4. Discuss if you think these online portraits of people are accurate. Explain your position.
  5. Explain if the prevalence of being exposed to social factors on social media influences individual behavior and the development of the social self, include how it does or does not. Use social psychological terminology to explain your answer.
  6. Discuss the positive and negative aspects associated with social media sites.

Use two to three scholarly resources to support your explanations.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

Benchmark Information

This benchmark assignment assesses the following programmatic competency:

MS Psychology

SOC 1.1: Describe how social factors in group and society influence individual behavior and the development of the social self.

Guillain-Barre Syndrome (GBS): Physiology- Variants and Treatments


Abstract

Guillain-Barre Syndrome (GBS) is a disease which causes damage in the peripheral nervous system. Guillain-Barre Syndrome refers to a group of disorders, including several variants such as acute inflammatory demyelinating polyradiculoneuropathy, acute motor axonal neuropathy, acute motor-sensory axonal neuropathy, as well as, Miller Fischer Syndrome.  The cause of Guillain-Barre syndrome is unknown; bacterial or viral infections can lead to the development of Guillain-Barre Syndrome. Due to molecular mimicry, the immune system attacks healthy cells instead of the infection and ultimately destroys the myelin sheath or axon. In the early stages, the Schwann cells make new myelin, but overtime this slows the impulses traveling down the axon. This demyelination or axonal damage in the peripheral nervous system leads to paresthesia, muscle weakness, impaired reflexes, speech and vision difficulties, orthostatic hypertension, and in some cases death. In order to diagnose Guillain-Barre Syndrome, a lumbar puncture is performed. Additionally, a Nerve Conduction Study (NCS) or electromyography (EMG) may be conducted. Treatment for Guillain-Barre Syndrome includes intravenous immunoglobins (IVIg) or plasmapheresis.


Keywords:

Guillain-Barre Syndrome, demyelination, immune system


Guillain-Barre Syndrome

Guillain-Barre Syndrome (GBS) is an autoimmune disease with annual incidence rates of one or two out of 100,000 (Craig, 2019). Guillain-Barre Syndrome (GBS) was first identified in 1859, when five patients presented with contemporary GBS symptomology (Donofrio, 2017). Since the eradication of Polio, GBS has become the number one cause of acute loss of muscle tone, weakness, and loss of reflexes worldwide (Donofrio, 2017). Overall, GBS is a rare disease, however it is one of the more common types of neuropathy. Guillain-Barre Syndrome has an average onset of forty years old and affects more males than females (Dimachkie & Barohn, 2013). Two-thirds of all cases are linked to a preceding infection (Dimachkie & Barohn, 2013). Additionally, the exact cause is unknown, but Guillain-Barre syndrome is most frequently preceded by exposure to an infection (Mayo Clinic, 2018). Overall, the risk of developing GBS within one’s lifetime is less than one in 1,000 (Donofrio, 2017).

Individuals with Guillain-Barre Syndrome experience symmetrical numbness and weakness in their lower limbs in the earlier stages. Additionally, individuals experience loss of reflexes and sensory abnormalities (Craig, 2019). The progression of symptoms varies from one individual to another, but in some cases the onset of weakness can be rapid resulting in quadriplegia within a few days (Donofrio, 2017). In most cases, the weakness begins distally and spreads proximally. In rare instances, the weakness is localized to the legs (Donofrio, 2017). Roughly half of all individuals with GBS experience facial weakness, and cranial nerve dysfunction (Wijdicks & Klein, 2017). When Guillain-Barre was first discovered, it was believed to be a single disorder. Over the last century of work, it is better understood as a group of disorders including the following: acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN), or acute motor-sensory axonal neuropathy (AMSAN), and Miller Fisher syndrome (MFS) variant. The classic presentation of GBS is acute inflammatory demyelinating polyradiculoneuropathy (AIDP) (Wijdicks & Klein, 2017).


Physiology of Guillain-Barre Syndrome


Causes of Guillain-Barre Syndrome

GBS is categorized as an acute polyradiculoneuropathy, which means its onset and progression is rapid and it affects the peripheral nerves. The diseases most associated with onset are Epstein-Barre Virus,

Mycoplasma pneumoniae

,

Cytomegalovirus

, and

Campylobacter jejuni

, among others (Dimachkie & Bahrohn, 2013).

Campylobacter jejuni

is a gastrointestinal infection, whereas, Epstein-Barre Virus,

Mycoplasma pneumoniae,

and

Cytomeglavirus

are respiratory infections. The introduction of an infection into the body results in an immune response which specifically targets the peripheral nerves (Willison, Jacobs, & Doorn, 2016). Within ten to fourteen days after a respiratory illness or gastroenteritis, GBS can occur (Donofrio, 2017).  Among all infections,

Campylobacter

is the most commonly identified. Antibodies aimed at attacking the

Campylobacter

antigen are among those most commonly found in cases of GBS (Donofrio, 2017). Aside from infections, there is controversy regarding other succeeding health concerns and GBS onset including Zika virus, surgery, pregnancy, and vaccinations (Donofrio, 2017). In a retrospective study on thirty-six adult patients with GBS, seventeen of them had symptoms of infection and four of them underwent surgery or trauma within six weeks prior to GBS diagnosis (Yang, Lian, Liu, Wu, & Duan, 2016). Overall, the researchers determined that GBS axonal type occurs more often post-surgery, as opposed to non-surgical or non-trauma patients (Yang et al., 2016).

The disease worsens due to what is known as molecular mimicry. The antigens from bacterial or viral infections appear similar to the lipids found in the myelin sheath, resulting in the immune system attacking those cells and ultimately destroying the myelin sheath. In the early stages, Schwann cells make new myelin, but overtime this slows the impulses traveling down the axon (Liu, Dong, & Ubogu, 2018). The succeeding events of this are largely unknown at this time (Willison, Jacobs, & Doorn, 2016). Additionally, the source of impairment, whether it be the myelin or axon is a marked difference among variants of the disease. Destruction of the myelin or axon leads to the clinical presentation of Guillain-Barre. This demyelination or axonal impairment in the peripheral nervous system leads to paresthesia, muscle weakness, impaired reflexes, speech and vision difficulties, orthostatic hypertension, gastrointestinal symptoms, and in some cases death (Willison, Jacobs, & Doorn, 2016). During the first two weeks, the disease progresses rapidly, and limb weakness becomes progressively worse. This worsening of symptoms also involves the sensory and cranial nerves. The facial nerve is involved in up to seventy percent of cases (Dimachkie & Barohn, 2013).


Guillain-Barre Syndrome variants


Acute inflammatory demyelinating polyradiculoneuropathy

Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is a type of Guillain-Barre and is the most common form within the U.S. This demyelinating type is characterized by muscle weakness in the lower limbs which spreads proximally (Mayo Clinic, 2018). In AIDP type, both the motor and sensory nerves are affected. Additionally, the myelin is predominately affected and minimal axonal damage occurs (Craig, 2019). The antigens involved are associated with demyelination due to macrophage cleanup (Wijdicks & Klein, 2017). Overall, there is a high likelihood of regaining functioning if patients have proper medical care (Willison, Jacobs, & Doorn, 2016).


Physiology.

In the acute inflammatory demyelinating polyradiculoneuropathy variant of GBS, otherwise known as demyelinating type, there is damage to the myelin sheath which surround the axons near white blood cells (Kloos, 2016; Kegelmeyer, Buford, & Heathcock, 2016). The complement system is activated. This is a part of the immune system most related to antibodies and phagocyte cells. The purpose of the complement system is the clear away debris and fight off infection by attacking the infection’s plasma membrane. T-cells are activated by this system which also activate macrophages which damage the myelin (Liu, Dong, & Ubogu, 2018). However, in AIDP, the disease mimics the normal anatomical makeup of peripheral nerves. This is known as molecular mimicry (Liu, Dong, & Ubogu, 2018). The disease tricks the immune system into attacking the myelin, when in fact the immune response is intended to attack the disease. As a result of this mimicry, the myelin sheath is destroyed, signal conduction is impaired, and normal functioning of the periphery is halted (Dimachkie & Barohn, 2013; Kloos et al., 2016).


Clinical Presentation.

For individuals with AIDP, their symptoms progress rapidly. Feelings of weakness occur on both the right and left side, in a symmetric fashion, and begin distally and progress proximally. In the majority of AIDP cases, roughly ninety percent experience muscle weakness which begins in the legs and progresses proximally. This weakness in the extremities is the result of demyelination of the axons. Electrical signals are unable to send properly. More specifically, these electrical signals, or action potentials, have a harder time traveling further distances. Hence, the weakness in the distal areas of the limbs in the earlier stages (Donofrio, 2017). This weakness continues to spread, eventually affecting the respiratory muscles. This progression of the disease is better explained by continued demyelination, and which further impairs the ability of signals to adequately send. Consequently, respiratory issues including respiratory failure can occur which is due to the rapid progression of symptoms and the impairment traveling from distal to proximal areas. This weakness extends to reflexes, specifically a general loss of reflexes in patients. Guillain-Barre Syndrome can also affect the autonomic nervous system which is linked to symptoms such as urinary retention or orthostatic hypertension (Willison, Jacobs, & Doorn, 2016). Over the duration of one to three weeks the disability progresses. The ability to walk independently is typically lost at the time of peak impairment (Fokke et al., 2014).




Acute motor axonal neuropathy and Acute motor-sensory axonal neuropathy

Acute motor axonal neuropathy (AMAN) and Acute motor-sensory axonal neuropathy (AMSAN), also known as the axonal type, are most associated with infections such as

Campylobacter Jejuni,

and more controversially, the Zika virus (Dimachkie & Barohn, 2013; Wijdicks & Klein, 2017). In the axonal form, patients are subject to more rapid deterioration and prolonged duration of paralysis as well as respiratory issues. These respiratory issues can escalate to respiratory failure over the course of a few days (Dimachkie & Bahrohn, 2013). Although the axonal type is less common within the U.S., this form is marked by immunoglobulins which target gangliosides (Mayo Clinic, 2018). Antigens of the bacterial and viral infections are subject to molecular mimicry which causes destruction of the myelin (Liu, Dong, & Ubogu, 2018).


Physiology.

In the axonal type, immunoglobulin G (IgG) antibodies and complement act directly against the cell membrane. Therefore, the damage is mediated by IgG antibodies in addition to the complement system (Dash et al., 2014). When an infection such as enters the system, its antigens mimic the normal anatomy of peripheral neurons, specifically the gangliosides. There are four key gangliosides, GM1, GD1a, GT1a, and GQ1b, each with different anti-ganglioside antibodies (Dash et al., 2014; Wijdicks & Klein, 2017). The immune system recognizes a foreign substance but instead of attacking the infection, the antibodies attack the gangliosides which are located within peripheral axons. Most commonly in the case of GBS,

Campylobacter

infection might enter the body which leads to a production of IgG antibodies against the bacterial cell wall substances. This cross reacts with nerve cell gangliosides. This attack on the axons leads to degradation and impairment (Dash et al., 2014).


Miller Fisher syndrome (MFS)

Miller Fisher Syndrome was the first variant of GBS. In this type of Guillain-Barre syndrome, paralysis begins behind the eyes as opposed to in the lower limbs (Mayo Clinic, 2018). Furthermore, MFS is associated with ataxia, loss of reflexes, ophthalmoplegia, among other abnormalities (Craig, 2019). This type is associated with alterations in consciousness. MFS is less common within the U.S. population. Generally, patients with MFS have two features of GBS along with elevated cerebrospinal fluid protein along and associated antibodies which informs diagnosis of GBS (Dimachkie & Barohn, 2013). In the Miller Fischer variant, the antibodies which attack normally occurring gangliosides are GQ1b and GT1a (Wijdicks & Klein, 2017). In this variant, the oculomotor nerves are affected which leads to paralysis or weakness in the eye area (Wijdicks & Klein, 2017) As with other type of GBS, molecular mimicry is responsible for this attack response which impairs the peripheral nervous system  (Liu, Dong, & Ubogu, 2018). It is possible for MFS to progress to GBS (Dimachkie & Barohn, 2013).


Treatment


Diagnosis

The best contributor to positive treatment outcomes is early detection. In addition to medical testing, patients presenting with Guillain-Barre syndrome are likely to display progressive weakness in all four limbs, specifically the arms and legs, including a loss of reflexes (Craig, 2019). Individuals presenting with such complaints are screened for a variety of disorders including GBS. In order to diagnose Guillain-Barre syndrome, a lumbar puncture, nerve conduction test, or electromyography is performed depending on the duration of symptoms and progression of the disease. Nerve conduction studies determine the subtype of GBS. If abnormalities are detected in motor neurons this is indicative of demyelinating type, whereas sensory neuron abnormalities are indicative of axonal type (Dash et al., 2014). Nerve conduction studies (NCS). In NCS, the nerves outside of the brain and spinal cord are stimulated through the use of electrodes placed on the skin. Both muscle and sensory nerve action potentials are recorded (Dash et al., 2014). This helps to identify the type of GBS, for example, axonal or demyelinating, while also providing information about the overall current functioning of the axons. In addition to NCS, electromyography tests muscles in response to stimulation. These studies generally show less muscle recruitment (Dash et al., 2014). Lumbar puncture is the standard procedure used to diagnose GBS, specifically, the prevalence of cytoalbuminologic dissociation, or increased levels of cerebrospinal fluid protein within the cerebrospinal fluid (Willison, Jacobs, & Doorn, 2016; Fokke, Berg, Drenthen, Walgaard, Doorn, Jacobs, 2014). This increase occurs because of the inflammation. Generally, individuals with GBS will have greater than 0.55 g/L of protein (Willison, Jacobs, & Doorn, 2016; Fokke et al., 2014). In addition, symmetrical weakness which travels distal to proximal, and progression of symptoms resulting in loss of reflexes are key factors for diagnosis as GBS symptoms can be similar to that of other disorders.


Challenges with Diagnosis

The symptoms of GBS overlap with a wide array of other medical disorders. Making early detection challenging, as other diagnosis may be suspected and screened for early on. For example, the symptoms of GBS can be similar to myasthenia gravis, stoke, or encephalitis, among others (Dash et al., 2014). Doctors are not likely to encounter GBS frequently throughout their career. This coupled with the various presentations can be diagnosis challenging, let alone early detection. The onset of GBS occurs overtime and as a result, serum analysis may not reveal CSF protein levels synonymous with GBS until several days after onset. Making diagnosis a challenging process (Dash et al., 2014).


Treatment Options

Treatment for GBS includes intravenous immunoglobins or plasmapheresis. The mechanism of action is not yet fully understood for these interventions (Liu, Dong, & Ubogu, 2018). Plasma exchange or intravenous immunoglobin speeds the recovery process, however, combination immunotherapy is not more effective (Wijdicks & Klein, 2017). Plasma exchange works by removing the specific inflammatory substances mediating the disease (Dimachkie & Barohn, 2013). Plasma exchange, or plasmapheresis, removes antibodies which contribute to the destruction of peripheral nerves  (Liu, Dong, & Ubogu, 2018). Intravenous Immunoglobulin (IVIg) acts to halt degradation of the peripheral nerves. IVIg introduces an anti-inflammatory effect throughout the periphery (Dimachkie & Barohn, 2013). Immunoglobulins aim to clear damaging substances from circulating in the peripheral nervous system (Liu, Dong, & Ubogu, 2018).


Future Directions

Since Guillain-Barre Syndrome was first identified, over a century of work in this area has led to a better understanding of the pathology of this disorder. In order to improve patient outcomes moving forward, research aimed at identifying biomarkers for disease severity are needed (Esposito & Longo, 2017). With proper treatment patients are able to have a full recovery, however a small percentage of patients still experience weakness three years later (Willison, Jacobs, & Doorn, 2016). A small proportion of patients experience weakness or tingling several years later.


References

  • Craig, A. (2019). Rehabilitation of Peripheral Neuropathy, Kansas City, Kansas: McGraw-Hill Education.
  • Dash, S., Pai, A. R., Kamath, U., & Rao, P. (2014). Pathophysiology and diagnosis of Guillain-Barre syndrome—challenges and needs.

    International Journal of Neuroscience, 125

    (4), 235-240. doi: 10.3109/00207454.2014.913588
  • Dimachkie, M. M. & Barohn, R. J. (2013). Guillain-Barre Syndrome and Variants.

    Neurol Clin, 31

    (2), 491-510. doi:10.1016/j.ncl.2013.01.005.
  • Donofrio, P. F. (2017). Guillain-Barre Syndrome.

    American Academy of Neurology, 23

    (5), 1295-1309. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/28968363
  • Esposito, S. & Longo, M. R. (2017). Guillain-Barre Syndrome.

    Autoimmunity Reviews, 16

    , 96-101. http://dx.doi.org/10.1016/j.autrev.2016.09.022
  • Fokke, C., Berg, B., Drenthen, J., Walgaard, C., Doorn, P. A., Jacobs, B. C. (2014). Diagnosis of Guillain-Barre syndrome and validation of Brighton criteria.

    Brain, 137

    , 33-43. doi:10.1093/brain/awt285
  • Kloos, A. D., Kegelmeyer, D. A., Buford, J. A., & Heathcock, J. C. (2016).

    Neurologic Rehabilitation: Neuroscience and Neuroplasticity in Physical Therapy Practice


    .

    Columbus, Ohio: McGraw-Hill Education.
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    Human Vaccines & Immunotherapeutics, 14

    (11), 2568-2579. https://doi.org/10.1080/21645515.2018.1493415
  • Mayo Clinic (2018). Guillain-Barre Syndrome. Retrieved from https://www.mayoclinic.org/diseases-conditions/guillain-barre-syndrome/symptoms-causes/syc-20362793
  • Wijdicks, E. F., Klein, C.J. (2017). Guillain-Barre Syndrome,

    Mayo Clinic, 92

    (3), 467-479. http://dx.doi.org/10.1016/j.mayocp.2016.12.002
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    Lancet, 388

    , 717-727. http://dx.doi.org/10.1016/ S0140-6736(16)00339-1.
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    Journal of Neuroimmunology

    , 17-21. http://dx.doi.org/10.1016/j.jneuroim.2016.02.003

Symptoms of Dementia


1.1


Dementia


Normal Ageing


Loss of Nerve cells

  • Due to loss of nerve cells and less cerebral cortex the cerebrum contracts.
  • Plaques and tangles cause the passing of nerve cells and disturb the messages in the cerebrum.
  • in the ordinary maturing cerebrum there are discovered a few tangles yet not in the substantial sum.
  • in the ordinary maturing transforming of data is slower yet just a little measure of nerve cell misfortune.


Slower reaction and decisions

  • The dementia customers are befuddled and not ready to settle on choices on self.
  • slower responses are impacts of plaques and tangles to memory and other range in the mind
  • •in ordinary maturing an individual may be slower however they can do their ADL’s themselves and they also settle on their own choices and ready to respond.
  • due to some nerve cells lost in ordinary maturing the conduction of messages by means of nerve pathway is slower which impact the responses.


Memory Changes

  • They may lose the capacity to perceive the names of companions, even those near them.
  • The dementia occupant can’t settle on choices and they experience issues in emulating the guidelines and their routine well.

in the ordinary maturing they find themselves able to perceive individuals and can standardize.

in ordinary maturing the customers have the capacity take after directions and there are frequently free.


Plaques and Tangles

  • Plaques are dead cells that are saved of protein assembled beta amyloid and the stick.
  • in the dementia customers there is bunches of plaques and tang
  • they have little measures of plaques and tangles in the cerebrum.
  • plaques and tangles are little in number as contrasted with the dementia customers which are not influencing anyth


1.2


a) Dementia and Delirium





Alertness:

  • In dementia customers their sharpness is general, they are generally ordinary.
  • In insanity customers the readiness vacillates, depleted and hyper vigilant.





Emotion:

  • In dementia customers they are shallow, thoughtless and shallow.
  • In insanity customers they are Irritable, forceful and dreadful.


Sleep:

  • In dementia customers they frequently have exasperates rest in throughout the night. They are wanderings all over and befuddled around evening time once in a while.
  • In insanity customers the perplexity exasperates slumber or may have store rest.


b


) Dementia and Depression





Memory and Comprehension:

  • In dementia, customer’s memory and comprehension are hindered. As infection advancement, long haul memory additionally influenced or lost.
  • In gloom the customers’ memory in some cases weakened. Long haul memory by and large in place and poor consideration.





Perception

  • In dementia customers observation is typical; their pipedreams are roughly 30-40%.
  • In gloom the customer’s recognition is sound-related; their pipedreams are roughly 20%.





Emotions:

  • In dementia customers they are shallow, fractious and lax.
  • In gloom: the patients are level, miserable, dreadful and touchy.


1.3


a) Alzheimer’s Disease

  1. Loss of memory is aftereffect of plaques and tangles in the mind that cause the passing of nerve cells. Loss of memory influence the everyday life exercises, for example, correspondence, exercises and security danger.
  2. Loss of weight may happen with Alzheimer’s malady. Case in point: a few patients overlook how to bite and how to swallow sustenance.
  3. There is less cerebral cortex which recollect this controls the cerebrum including memory, cognizance, and discourse in Alzheimer’s patient.
  4. The surfaces of the cerebrum adjust and mind cells shrink. There are more plaques looked at inside the typical more seasoned individuals. The liquid filled spaces of the mind increment in size.
  5. People with Alzheimer’s illness have change in their character. For instance: an individual who was obliging and cordial when he has infection will get to be forceful, irate and upset.


b) Vascular dementia

  1. Vascular dementia is brought about when a vascular occurrence happens denying cerebrum of a sufficient supply of blood and oxygen, bringing about the passing of cerebral tissue.
  2. The patients with vascular dementia have passionate switch all over.
  3. The patients change in discourse. They talk slower and experience issues in talking.
  4. The Patients have disturbance to transient memory, association of contemplations and state of mind.
  5. Vascular dementia patients experience issues in strolling.


c) Lewy Body Disease

1. This is brought about by a strange vicinity of cerebral cells called Lewy bodies which found all through the mind what creates inside nerve cells. It is believed that these may help the demise of the cerebrum cells.

2. They have tremors and solidness like Parkinson’s illness.

3. Memory misfortune: likes other dementia infections. The patients with lewy body illness have influence to short- term and long haul memory.

4. The patients experience issues with fixation and consideration.

5. The patients experience issues judging separations, regularly bringing about falls.

  1. The most noteworthy danger element is age. The number individuals found with dementia the age of sixty-five. As the nerve cells got harmed in the mind.
  2. Other component can from way of life, for example, hypertension and coronary conduit ailment.
  3. The patients have a conceivable hereditary connection that inherited from past era. Case in point if a guardian or kin has a dementia then the persons


1.5


Cognitive effects

  • cognitive impacts lead to dementia patients experience issues with transient memory which can impacts both to individual living with dementia and the individuals around them, for example, a few patients are troublesome after discussion and helping. They are likewise experience issues thinking and are effectively diverted.
  • the patients will have poor ability to know east from west or off and on again loses their ability to know east from west: they experience issues to discover the courses (go to lavatory, can).


Functional effects

  • The practical capacity of the customer changes like they experience issues in dressing and different capacities.
  • They need to remind to consume, wash, dress and utilize the latrine and in addition needs help overseeing every day tasks.


Behavioral effects

  • They experience difficulty with level of individual cleanliness and dress sense lead to other individuals may be humiliated with somebody’s close to home cleanliness or dress sense and would prefer not to be seen with the individual.
  • Their verbal relational abilities are likewise influenced that makes the individuals living with dementia hard to express the things so they begin communicating their needs in some different ways.


Psychological effects

  • psychological impacts prompts the patients have changes in their conduct, for example, they get outrage and dissatisfaction and melancholy and in addition they detach themselves and abstain from going out as they discover it excessively hard to deal with the clamor and the other individuals.
  • They lose the inspiration for all exercises of every day living, additionally they feel bore and may have visual mental trips.


2.1

1. Relationship:

Dementia patients ought to dependably have associations with relative, companions and help suppliers that is in charge of the social, profound and passionate prosperity. Relationship has an essential part for supporting the dementia patients and it can be produced amid consistently minds and in addition amid sorted out exercises. Help supplier ought to admiration and comprehend dementia conduct. Help supplier and relatives of patients need to keep up their association with dementia customer so that the customer will adapt better and feel valued.

2. Correspondence:

Correspondence helps the customer to express about their needs, in the same way as or abhorrence. At the point when speaking with the individual with dementia, compelling relational abilities and non-verbal communication need to be utilized. Help supplier ought to talk obviously, utilizing eyes contact, don’t hurry. As an issue with dementia encounters a progressive abatement in capacity to convey.

3. Individuality:

Help supplier ought to treat customers exclusively that implies help supplier help every customer similarly and regard them. Case in point, help supplier ought to give customer decision about what they like, for example, garments they need to wear, which exercises they like to do or take an interest. In addition empower the customer’s freedom however much as could be expected.

4. Feeling:

Help supplier need to concentrate on the uniqueness and the rich scope of sentiments and feelings of the individuals living with dementia. Guardians ought to invest time with customers and sway them to discuss their emotions and comprehend them. Anyway dependably utilize a cool methodology to recognize customer’s emotions.

5. Abilities Retained

From consideration arrangement, help supplier ought to recognize what exercises they used to like previously. Despite the fact that they are not ready to do the exercises yet the guardians ought to urge the customers to be as autonomous as would be prudent and inspire them to join the exercises of the rest home. Likewise they ought to fare thee well that the customers are getting a charge out of the exercises.

6. Needs of the person with dementia:

Physical needs: Person with dementia need guarantee physical needs, for example, consuming, shower, dressing or wear glasses on the grounds that they are not ready to help themselves.

Psychological needs: Person with dementia need somebody can convey and comprehend their inclination. Somebody can converse with them and offer with dementia patients.

2.2

  • Individuality influences PCC of dementia patients. Help supplier ought to take a gander at forethought arrange and realize what they can do, what they like to do and provide for them. Help supplier ought to provide for them what exercises they like to do.
  • Relationship has a part essential for dementia patients. The dementia patients ought to stay in great association with relatives, help suppliers and companions. Relationship for an individual with dementia needs to be minding and trusting on the grounds that just with connections they can adapt better to their malady and feel esteemed and adored.
  • Following the consideration arrangement, help suppliers need to verify that they comprehend and have learning about quiet’s inclination. Help supplier ought to know how to adapt to customers when they get irate or steamed, cool off patients and fulfill them feel.

2.3

Genuine movement makes opportunities for individuals living with dementia to react fittingly notice use their capacities. Importance exercises will develop with feeling, relationship and feelings. Compelling exercises can trigger memory and capacities. Genuine exercises may be not quite the same as one patient to other patient.

1. Verbal:

The customers with dementia have diminishes the correspondence capacities that gets to be most noticeably bad with the progression of time as they are not by any means ready to talk or talk legitimately. They have hard to discover the right word or stuck on the words. They may rehash the same word or expression again and again. They may experience issues in communicating feelings.

2. Vocalization:

The customers with dementia can’t talk so they convey what needs be by the method for tedious discourse, groaning, creaming and singing. For instance if the customer feels torment then they were shouting or vocalizing. Vocalizations may be troublesome and offensive for others.

3. Gestures:

Dementia customers they utilize signals for consideration or say something to help laborer by the motions, for example, tapping, indicating, waving or nodding. The motions of every customer have an alternate significance. For instance when the customer needs to strive for latrine they are tapping on the seat and on the off chance that they need to consume something then they utilize the motion with hands and development of the mouth.

4.Communication aids Communication helps is things helping correspondence in the middle of guardian and customer with dementia, for example, picture book, music, blaze cards. Case in point: a few customers utilize the cards with where they need to strive for visit. Picture book can indicate what they need. In addition, if an individual is not ready to talk that individual may utilize a board to compose words on.

3.2

1. Sensory losses

The lost of sight and listening to prompt trouble in correspondence with dementia patients. They will misfortune association with other individuals. Case in point: without glasses, they are can’t see non-verbal communication and not able to get significance of correspondence.

2. Communication accomplice:

The correspondence accomplices are the individuals who help the dementia customers in correspondence and may be they are not accessible at constantly. The correspondence accomplices may be life partner, relative or companions.

3. Health status:

Infections and sicknesses will have a terrible impact on correspondence capacity of dementia patients, for example, Parkinson’s ailment and stroke, the patients will have hard to talk obviously.

4. Environment:

Environment can be a correspondence obstruction as it influences the correspondence of the individuals with dementia, for example, extensive loud environment, individuals in a room or close-by talking excessively boisterous or excessively quick, and absence of powerful correspondence expertise among human services help laborers.

5. Culture:

Society is a variable that additionally influences to correspondence, for example, stress, utilization of motions. Frequently, dementia patients talk their dialect or help laborers don’t comprehend the dialect of customers. For instance: Arabic individual conversing with help laborer in it dialect.

6. Age:

Now and again its truly hard to comprehend the needs of dementia customers for the more youthful parental figures when the dementia customer chatting with more youthful individual. As some of more youthful they talk quick or talk in more youthful statement consequently the dementia customer misjudged. Elderly age can relate with tangible misfortune and influence to correspondence.

7. Gender:

Sexual orientation additionally has impact on correspondence as some male patient use distinctive words with female. This could be a sex boundary like Female patients can without much of a stretch impart their story and issues than male patients.

8. Reverting to original language:

At times an individual with dementia talk will return to unique dialect and may review words that others don’t comprehend which can be a boundary there would be an issue if no translator is accessible.

9. Expressive and reciptive correspondence issue:

The patients with dementia can’t discover words to convey. They are not able to express what they need.

Open is the point at which they don’t comprehend what impart to them, verbal and non-verbal correspondence.

3.3

1. Communication partner

Help laborer ought to peruse consideration arrange and verify accomplices are presented with patient. In addition, help specialist verify that patient with dementia are agreeable with correspondence accomplices.

2. Environment:

Verify customer with dementia they are agreeable and commonplace questions in their room. In the event that he/she feels good then put sign and images which can be helpful like on the off chance that he needs to go can then he put the finger on the sign. Verify give the sufficient lighting and proper space for moving the customer.

3. Verbal and non-verbal:

Help specialist verify that they talk gradually, obviously to patients with dementia to comprehend the non-verbal correspondence, help laborer ought to utilize eyes contacts.

4. Singing:

Singing is a system to empower patients with dementia correspondence. Help specialist ought to search for a few melodies in the past which help dementia patient to bring the gorgeous memory. Singing help to quiet down patient with tension and bring back cheerful memory.

5. Music:

Music sways dementia patient to impart. Music can lessen tension, unsettling and cool off dementia understanding. Some music can be utilized with fundamental activity of arms or legs that likewise amuse them and urge them to do exercise.

6. Activities:

Exercises in day by day living can sway dementia patient to correspond with others. Exercises help communicating their inclination, diminishing uneasiness, provide for them upbeat time. It can provide for them compelling things to discuss and can help to determination unfinished business.

7. Communication helps:

Photos, new paper cuttings, memory books all energize correspondence on the grounds that dementia patient can utilize straightforward signs structure them to impart. Checking vision and portable hearing assistants are likewise paramount.


  • PUSHPINDER KAUR

Establishment of Non-Opioid Directives and Coverage of Non-Opioid Therapy

This paper will discuss advocacy for Ohio Senate Bill 51 which aims to establish a Non-Opioid Directive and coverage of evidence-based Non-Opioid therapies by certain insurance carriers (S.B. 51, 2019).  This Bill was chosen due to the catastrophic opioid crisis that currently exists in the State of Ohio.  An overview of healthcare policy and advocacy, identification and solution of the healthcare policy concern and identification of an elected official to present this information to will be explored.


Overview of Healthcare Policy

According to the World Health Organization ([WHO], 2019), “Health policy refers to decisions, plans, and actions that are undertaken to achieve specific health care goals within a society.”  Government policies are in place to serve as regulatory guidelines within many different industries including healthcare.  Policy and law provide the framework to dictate the behavior of individuals and organizations in order to improve how healthcare is delivered resulting in better public health (Teitelbaum & Wilensky, 2017

).



Nurses work on the frontline within all health care settings.  This provides nurses with the unique opportunity to recognize what best practices are not working and the knowledge to develop new policies in order to improve patient care, patient safety and ultimately the health of the community.  As stated by The American Nurses Association (ANA) Code of Ethics, nurses in all roles and settings should strive to advance our profession by conducting research and scholarly inquiry, by developing professional standards and by generating nursing and health policy (American Nurses Association, 2015).

Patient advocacy is one way in which nurses can execute the provisions outlined by the ANA’s Code of Ethics.  Merriam-Webster (2019) defines advocate as one who pleads the cause of another; specifically: one who pleads the cause of another before a tribunal or judicial court.  Since nurses spend the most time with patients, we have insight on what is working well and what is not.  Our experiences with patient care provides us with the information to identify problems within our current healthcare system.  If we then share those experiences and our insight with elected and/or public officials, we can advocate for our patients and get involved in the policy-making process.  Advanced Practice Nurses have the knowledge and experience to promote health, advocate for increased access to care, reduce health disparities and help shape the health delivery system by getting involved in policy processes (American Associations of Colleges of Nursing, 2011).


Identification of Healthcare Concern

The healthcare concern I have chosen to address is the current opioid crisis in the State of Ohio.  While the Opioid crisis is present across the United States, it has hit Ohio especially hard.  Ohio had the second highest rate of opioid related overdose deaths in the United States in 2017 with 947 deaths attributed to prescription drugs and 3,523 deaths attributed to synthetic opioids such as fentanyl.  Heroin-related deaths also increased from 139 in 2012 to 3,523 in 2017 (The National Institute on Drug Abuse, 2019).

So of course we ask, how did we get here?  In the 1990’s, pain was implemented as the fifth vital sign in an effort to improve the treatment of pain.  Unfortunately, this lead to physicians overprescribing opioids for pain (Anson, 2016).  Of course this was supported by the pharmaceutical companies who assured the medical community that opioid therapy was safe for their patients and the patients would not become addicted.  Extended-release oxycodone (OxyContin) was introduced in 1996 with the manufacturer claiming that it was not as addictive.  As opioid medications became more difficult to prescribe and dispense, the synthetic opioid Fentanyl gained popularity due to its potency and decreased manufacturing cost (National Institute on Drug Abuse, 2019).  Overtime of course we learned that patients were becoming addicted and began using opioids to self-medicate.  At the start, these medications could be obtained quite easily.  Over time as we learned that misuse and addiction had become a problem, policies were changed making it difficult for patients to obtain the amount of medications they had become accustomed to taking.  This led to patients “doctor shopping” and visiting multiple emergency rooms in an effort to receive prescriptions from multiple providers (National Institute on Drug Abuse, 2015).  With the implementation of prescribing limits and the use of Prescription Monitoring Programs, patients started switching to illicit drugs like heroin which is cheap and can be easily obtained (Centers for Disease Control and Prevention, 2014).

The opioid crisis affects a broad spectrum of users.  It is present in the city, the suburbs and rural areas.  There is no discrimination in regards to age, demographic, social status or race.  The switch from prescription opioids to illicit drugs comes with deadly consequences.  Street drugs do not provide a label with the contents which makes them extremely dangerous and often times deadly.  Heroin, fentanyl and carfentanil can be immediately deadly.  A user may buy what they were told is heroin and it may actually be fentanyl which can cause death instantly.  The same thing can happen with heroin that is too pure, carfentanil or synthetic drug versions which is certainly evident in the overdose rates (Higgs, 2016).


Solution to Healthcare Concern

Although often used as the first line of treatment, opioid use has not been shown to be effective in the treatment of chronic pain. (Schneiderhan, Clauw & Schwenk, 2017).


Evidence suggests thatnon-opioid therapies and treatment options are often much more effective and do not run the risk of addiction.  However, non-opioid treatment options are often not covered treatment options by insurance and patients cannot afford the out-of-pocket expense.  For example, Ohio Medicaid does not cover some non-pharmacologic evidence-based therapies.  Another issue is that Ohio healthcare providers are not properly trained in regards to appropriate pain management or addiction because the training is not required.  This more than likely limits the use of non-opioid therapies along with non-pharmacologic methods (Stevens & Akah, 2018).  Due to these facts, the healthcare solution that I have chosen to advocate for is the establishment of non-opioid directives with coverage of non-opioid therapy, Senate Bill 51 (S.B. 51, 2019).  The State of Ohio is in a serious opioid crisis and I believe the passage of this Bill will make a difference.

There are a multitude of alternative therapies available for pain management that are often not utilized.  Non-pharmacologic therapies such as acupuncture or yoga may decrease pain.  Known barriers for these treatment options include limited access to these services and poor reimbursement.  The patient may also be opposed to these treatment options and demand pharmacologic treatment including opioids if they have had any amount of pain relief with their use in the past.  The patient resistance may also be due to a knowledge deficit or lack of encouragement for other treatment options by their providers Schneiderhan, Clauw, & Schwenk, 2017).  If Senate Bill 51 was passed, health insurance companies would be required to provide coverage for “evidence-based therapies that do not require the use of opioid analgesics in the treatment of pain.”  The bill also proposes the development of a non-opioid Directive form within one year of its effective date.  The non-opioid Directive form would specify that the patient does not wish to be offered, administered, prescribed, or provided an opioid analgesic as means for therapy.  If a non-opioid Directive was in place it would require prescribers to offer other means of therapy before treatment with an opioid analgesic occurs (S.B. 51, 2019).

The implementation of S.B. 51 would require education for providers as well as patients and families.  Healthcare providers would need to increase the utilization of non-opioid evidence-based pain management options and would need to provide patient education regarding these non-opioid therapies.  This would first require education for the providers along with improved insurance coverage.  Providers should also be required to complete mandatory continuing education with regards to proper pain management (Stevens & Akah, 2018).  In order to determine if S.B. 51 was effective, patients who were prescribed or ordered non-opioid medications and/or therapies would have to be followed in order to conclude if these options were effective in treating their pain.  With success of these options, a decrease in opioid users should also be evident.


Identification of Elected Official

State Senator Tina Maharath (D-Columbus) represents the 3rd Senate District and is serving her first term in the Ohio Senate after being elected to the General Assembly in November 2018.  She was chosen as the elected official to interview because she is the main sponsor of Senate Bill 51 (S.B. 51, 2019).


Conclusion

The current opioid crisis occurring in our country is one of the greatest public health crises of our time.  The State of Ohio has been hit especially hard and was ranked second highest in the rate of opioid related overdose deaths in the United States in 2017 (National Institute on Drug Abuse, 2019).  The problem started in the 1990’s when pain was added as the fifth vital sign in order to improve the treatment of pain which led to the overprescribing of opioids by physicians (Anson, 2016).  It was soon realized that patients were becoming addicted to these medications even though the drug companies said they were “safe.”  When this reality come to light changes were made limiting the prescribing of opioids which decreased access for patients.  Unfortunately, that led many patients to switch from legal to illicit drugs fueling our opioid crisis with devastating effects.  In addition to addiction treatment, healthcare providers need to rethink how they treat pain.  The old habit of prescribing opioid therapy as the first line of treatment for pain is no longer best practice.  Another important step is to be proactive by utilizing prescription drug monitoring programs in order to identify suspicious patterns of opioid use.  We also need insurance companies to start covering effective, evidence-based non-opioid pain remedies.  The underinsured could benefit from an expansion of coverage through the Affordable Care Act which would help to increase access for preventive care and possibly eliminate the need for painkillers.  Nurses have the knowledge and the power to advocate for their patients and can lobby for change.  It is our responsibility to do so in order to improve patient outcomes and promote healthy communities.  S.B. 51 can certainly promote change in the right direction.  By promoting the use of non-opioid treatment for pain, we can expect to see improved patient outcomes and less devastation caused by opioid use and abuse.


References

Meningitis Due To Intravenous Immunoglobulin Therapy


Acute Aseptic Meningitis Due To High Dose Intravenous Immunoglobulin Therapy for Guillain-Barré Syndrome

Abstract

The majority of adverse reactions of intravenous immunoglobulin (IVIG) therapy are mild, transient and self-limiting; however, potentially serious complications are rare and occur in less than 5% of patients receiving IVIG therapy. IVIG associated transient aseptic meningitis is an uncommon adverse effect and this phenomenon has been seldom described in literature. We report a case of aseptic meningitis due to high dose IVIG therapy in a Guillain-Barré syndrome (GBS) patient. The cerebrospinal fluid (CSF) analysis revealed high cell counts with predominance of lymphocytic cells, raised protein, normal glucose level and no growth of the organism on culture. He was managed symptomatically with adequate hydration and analgesic. Our patient improved without neurological complications. This case emphasizes the importance of recognizing IVIG associated neurological complications in GBS patients.

Keywords

Aseptic meningitis; Guillain-Barré syndrome; Intravenous immunoglobulin

Introduction

Intravenous immunoglobulin (IVIG) therapy is recommended in Guillain-Barré syndrome (GBS) patients. The majority of adverse reactions of IVIG therapy are mild, transient and self-limiting; however, potentially serious complications are rare and occur in less than 5% of patients receiving IVIG therapy. According to Kemmotsu et al., IVIG associated transient aseptic meningitis is an uncommon phenomenon occurring in about 1% of patient.

The common adverse effects are headache, nausea and vomiting, myalgia, low backache, tachycardia, mild grade fever and flushing. The serious complications are aseptic meningitis, thromboembolism, transverse venous sinus thrombosis, myocardial infarction, acute stroke, acute encephalopathy, posterior reversible encephalopathy syndrome, anaphylactic reaction, acute renal failure and serum sickness. IVIG associated transient aseptic meningitis is a very rare complication. Our patient developed aseptic meningitis following intravenous immunoglobulin therapy.

Case Presentation

A 14 years old boy presented with two days history of acute onset pure motor, progressive, symmetric, areflexic, flaccid quadriparesis without bladder/bowel, bulbar, respiratory symptoms or autonomic dysfunction. He had no history of fever, preceding illness of diarrhea, respiratory tract infection or any toxin exposure. A clinical diagnosis of Guillain-Barré syndrome (GBS) was made with Hughes Disability Scale 4. Nerve conduction study was suggestive of pure motor, predominantly demyelinating affection of right ulnar, bilateral median, bilateral tibial and bilateral peroneal nerves. Electrocardiogram (ECG) and serum potassium level were normal and urinary porphobilinogen was negative. Clinical profile and electrophysiological parameters fulfilled the Asbury criteria of GBS.

Intravenous immunoglobulin was given according to the recommended dose (0.4 mg/kg/day). His weight was 45 kg and total 90 gm IVIG was planned over five days in divided doses. On the fourth day, after receiving 72 grams of IVIG infusion, the patient developed progressive worsening headache, neck pain and recurrent vomiting. There was no history of fever, loss of consciousness or visual symptoms.

His temperature was normal. On neurological examination, meningeal signs: neck rigidity, Kernig signs and Brudzinski signs were positive. Bilateral fundi were normal. There were no other focal neurological signs.

Investigations

Hemogram and blood biochemistry were within the normal range. Blood culture was sterile. X-ray chest was normal and Mantoux test was negative. Lumbar puncture showed normal opening pressure and cerebrospinal fluid (CSF) analysis revealed pleocytosis (Total cell counts: 180 cell/dl) with lymphocytic predominance (85%), raised protein (110 mg/dl), normal sugar (56 mg/dl) and normal chloride (111 mEq/L) levels. CSF gram stain, AFB stain, KOH preparation, India ink and CSF culture for bacteria and fungi were negative. CSF TB PCR and HSV PCR were negative. MRI brain with gadolinium contrast was normal (Figure 1).

Differential Diagnosis

Diagnosis of acute aseptic meningitis was based on clinical features, CSF findings, negative viral markers and negative culture. The diagnosis of IVIG associated aseptic meningitis was made as there was a strong temporal relationship between onset of aseptic meningitis and high dose IVIG therapy; the extensive search for other causes of meningitis was negative and the improvement of symptoms within few days. However, possibility of viral meningitis was also thought, but absence of prodromal symptoms, no identifiable rise in serum viral titres and self-improvement of symptoms ruled out the possibility of viral meningitis.

Treatment

His symptoms were managed with hydration and analgesics. No antibiotic or antiviral therapy was given. A very slow infusion of IVIG was continued under strict supervision until completion of full dose therapy on the next day. The signs of meningeal irritation-neck rigidity, Kernig’s signs and Brudzinski signs disappeared over next two days.

Outcome

The patient was discharged in stable condition with Hughes GBS Disability Scale 1. He recovered completely without any neurological sequelae. He was asymptomatic after three months of followup.

Discussion

The exact pathophysiology of IVIG induced aseptic meningitis is not clear. The various postulated mechanisms of IVIG associated aseptic meningitis are direct toxic effect, immunologic drug hypersensitive reaction, allogenic immunologic reaction, hypersensitivity reaction to various stabilizing agents and cytokine release triggered by the therapy. Wada et al. showed the excitotoxic effect of IVIG in acute encephalopathy following IVIG therapy.

The IgG is an active ingredient of intravenous immunoglobulin capable of crossing the blood-brain barrier, penetrates the meninges, and enters the brain parenchyma.

In our patient, aseptic meningitis developed after 72 hours of initiation of IVIG. However, in literature, most patients developed aseptic meningitis within 48 hours of beginning IVIG therapy. According to Jarius et al., aseptic meningitis was frequently associated with polymorphic pleocytosis in the CSF examination; however, our patient had lymphocytic pleocytosis.

Most of the side effects associated with IVIG are mild, self-limited and related to the infusion rate and no specific therapy is required. Risk factors for IVIG associated aseptic meningitis are history of migraine and rapid, high dose infusion of IVIG. Slower infusion rate, proper hydration, antihistamines and analgesics may help to prevent mild reactions. Systemic steroid may be required in severe cases. Our patient was under strict supervision and no medical treatment was given. He improved without any neurological complications.

Headache and fever are well-recognized side effects of high dose IVIG, aseptic meningitis has rarely been reported in the literature in GBS patients. A high index of clinical suspicion should be kept for IVIG induced aseptic meningitis and should be confirmed by careful neurological examination and CSF analysis.

Take-Home Message

  • Acute aseptic meningitis may develop as a transient, self-limiting complication of high dose IVIG therapy in GBS patient.
  • Early recognition and management is required to prevent permanent neurological sequelae.
  • IVIG therapy should be continued in mild aseptic meningitis as the IVIG infusion is a life saving drug for GBS patient, at a slow infusion rate, with proper hydration, histamines and analgesics.
  • This case emphasizes the importance of recognizing IVIG associated neurological complications in IVIG treated GBS patient.

References

Figure Legends

Figure 1. Normal MRI brain with gadolinium contrast

Can you complete this | Law homework help

Scenario

The Friendly Dawg is a retail pet supply store owned by Dave Dawgs. Dave has worked in the store since high school and took over running the store after his father died two years ago. Originally the store sold only pet food and supplies, such as animal food, bird cages, water bowls, pet beds, and so forth. Upon taking ownership, Dave added fish tanks with fish for sale. Recently he built a kennel and cages in a former storage area in the rear of the store in order to sell live animals, such as snakes, birds, dogs, and cats. Landlord Lou came by during renovations and asked what was going on. One of Dave’s employees told Lou that The Friendly Dawg was expanding its inventory and needed the space. Landlord Lou told the employee, “Very exciting! Good luck!”

A few weeks later, landlord Lou began receiving complaints from the neighboring tenant, the Sunshine Yoga studio, that the noise from the dogs and parrots was very disruptive.

The signed lease between Dave Dawg’s deceased father and Lou describes the business as a pet supply store only and does not mention selling live animals. The lease specifies a rent in the amount of $500 a month. Sunshine Yoga does not have a written lease. The owner of Sunshine Yoga, Jasmine, met Lou one night in a bar two years ago where he verbally offered to rent her the space for $300 a month. Jasmine claims that landlord Lou told her that night that she could rent from him forever and that he would never evict her.

Lou called Dave, asking him to quiet the animals. Dave said he would try, but the complaints from Jasmine continued. Dave also demanded that Lou improve the air-conditioning system, claiming it was too hot in the rear of the store for his animals and it was causing them to become agitated. Landlord Lou refused, claiming that air-conditioning was not meant to cool that area and it was not his job as landlord to take care of live animals.

Dave stopped paying his rent, claiming that he was not obligated to do so because Lou was breaching his obligation under the lease to maintain the property in good repair. The next day, a dangerous snake escaped through the air vents and slithered into the neighboring yoga studio, frightening Jasmine, the owner, such that she had a heart attack.

After recovering, Jasmine stopped paying her rent, claiming that the premises were unsafe due to the presence of wild animals. She also claimed that she has been very depressed and anxious as a result of the ongoing situation. And she contends that she has lost clients because of the noise coming from The Friendly Dawg.

The Friendly Dawg has been a good tenant, enjoys a strong customer base, and pays more in rent than Sunshine Yoga. Sunshine Yoga has always been late with rent, and Jasmine constantly bothers Lou over minor issues.

Directions

Write two short papers—one on contract law and one on tort law.

Contract Law

Evaluate the potential rights, claims, defenses, obligations, and remedies for each party from the perspective of contract law. Determine whether landlord Lou has a right to evict either party. Use reliable resources, such as the textbook and other course resources, to support your evaluation. Specifically, include the following components in your evaluation:

Contract between The Friendly Dawg and landlord Lou

Analyze the scenario to determine whether a valid contract still exists between The Friendly Dawg and landlord Lou.

Explain the elements of a valid contract, and identify which contract elements, if any, exist between The Friendly Dawg and landlord Lou.

Analyze the potential rights, claims, defenses, obligations, and remedies available to both landlord Lou and The Friendly Dawg in this scenario.

Support your analysis by referencing specific legal principles or laws.

Contract between Sunshine Yoga and landlord Lou

Analyze the scenario to determine whether a valid contract still exists between Sunshine Yoga and landlord Lou.

Explain the elements of a valid contract, and identify which contract elements, if any, exist between Sunshine Yoga and landlord Lou.

Analyze the potential rights, claims, defenses, obligations, and remedies available to both landlord Lou and Sunshine Yoga in this scenario.

Support your analysis by referencing specific legal principles or laws.

Grounds to evict

Describe whether, based on your analysis of each party’s rights and obligations, landlord Lou has the grounds to evict either The Friendly Dawg or Sunshine Yoga.

Support your conclusions by referencing specific legal principles or laws.

Include a References section and cite your sources using APA style.

Tort Law

Evaluate the implications of tort law in this scenario and what legal claims Sunshine Yoga might have. Use reliable resources, such as the textbook and other course resources, to support your evaluation. Specifically, include the following components in your evaluation:

Tort law: Define what tort law is and how torts may affect business practices.

Relevant tort laws: Identify tort laws relevant to the scenario, specifically the incident involving the snake.

Legal claims

Identify what legal claims Sunshine Yoga might have against The Friendly Dawg and landlord Lou, based on those tort laws and related legal principles.

Support your conclusions by referencing the applicable tort laws and related legal principles.

Include a References section and cite your sources using APA style.

What to Submit

To complete this project, you must submit the following two papers:

Contract LawYour submission should be a 2- to 3-page Word document with 12-point Times New Roman font, double spacing, and one-inch margins. Sources should be cited according to APA style.

Tort LawYour submission should be a 1- to 2-page Word document with 12-point Times New Roman font, double spacing, and one-inch margins. Sources should be cited according to APA style.